Literature DB >> 10363948

The phenotypic characteristics of heterozygous reeler mouse.

P Tueting1, E Costa, Y Dwivedi, A Guidotti, F Impagnatiello, R Manev, C Pesold.   

Abstract

Histological and behavioral traits are associated with reelin (Reln) haplo-insufficiency in heterozygous reeler mouse (rl+/-). These phenotypic traits are an approximately 50% decrease of brain Reln mRNA and Reln protein, an accumulation of nicotinamide-adenine dinucleotide phosphate-diaphorase (NADPH-d)-positive neurons in subcortical white matter, an age-dependent decrease in prepulse inhibition of startle (PPI), and neophobic behavior on the elevated plus-maze. Possible analogies between these rl+/- phenotypic traits and signs of psychosis vulnerability are discussed.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10363948     DOI： 10.1097/00001756-199904260-00032

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  67 in total

1.  Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells.

Authors:  N R Smalheiser; E Costa; A Guidotti; F Impagnatiello; J Auta; P Lacor; V Kriho; G D Pappas
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-01       Impact factor: 11.205

Review 2.  Epigenetic GABAergic targets in schizophrenia and bipolar disorder.

Authors:  A Guidotti; J Auta; Y Chen; J M Davis; E Dong; D P Gavin; D R Grayson; F Matrisciano; G Pinna; R Satta; R P Sharma; L Tremolizzo; P Tueting
Journal:  Neuropharmacology       Date:  2010-11-11       Impact factor: 5.250

3.  Assessment of cognitive function in the heterozygous reeler mouse.

Authors:  Dilja D Krueger; Jessica L Howell; Britni F Hebert; Peter Olausson; Jane R Taylor; Angus C Nairn
Journal:  Psychopharmacology (Berl)       Date:  2006-09-15       Impact factor: 4.530

4.  Reelin protects against amyloid β toxicity in vivo.

Authors:  Courtney Lane-Donovan; Gary T Philips; Catherine R Wasser; Murat S Durakoglugil; Irene Masiulis; Ajeet Upadhaya; Theresa Pohlkamp; Cagil Coskun; Tiina Kotti; Laura Steller; Robert E Hammer; Michael Frotscher; Hans H Bock; Joachim Herz
Journal:  Sci Signal       Date:  2015-07-07       Impact factor: 8.192

5.  An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability.

Authors:  L Tremolizzo; G Carboni; W B Ruzicka; C P Mitchell; I Sugaya; P Tueting; R Sharma; D R Grayson; E Costa; A Guidotti
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-12       Impact factor: 11.205

6.  Cysteamine treatment ameliorates alterations in GAD67 expression and spatial memory in heterozygous reeler mice.

Authors:  Ammar Kutiyanawalla; Wanwisa Promsote; Alvin Terry; Anilkumar Pillai
Journal:  Int J Neuropsychopharmacol       Date:  2011-07-22       Impact factor: 5.176

7.  Nicotine restores Wt-like levels of reelin and GAD67 gene expression in brain of heterozygous reeler mice.

Authors:  Emilia Romano; Andrea Fuso; Giovanni Laviola
Journal:  Neurotox Res       Date:  2013-02-06       Impact factor: 3.911

Review 8.  Pharmacology of epigenetics in brain disorders.

Authors:  Pritika Narayan; Mike Dragunow
Journal:  Br J Pharmacol       Date:  2009-12-15       Impact factor: 8.739

Review 9.  Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects.

Authors:  Maarten van den Buuse
Journal:  Schizophr Bull       Date:  2009-11-09       Impact factor: 9.306

10.  Serotonin transporter clustering in blood lymphocytes of reeler mice.

Authors:  Tania Rivera-Baltanas; Raquel Romay-Tallon; Iria G Dopeso-Reyes; Héctor J Caruncho
Journal:  Cardiovasc Psychiatry Neurol       Date:  2010-04-21
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.