INTRODUCTION: The Clock Drawing Test (CDT) has been used in recent years as a simple neuropsychological instrument to assess cognitive deterioration associated with dementia, even though uniform operative criteria with respect to its application and scoring have not been established. OBJECTIVE: To present application normatives and establish the most relevant psychometric criteria of the CDT in a sample of healthy subjects (HS) and patients with Alzheimer's disease (AD). PATIENTS AND METHODS: 56 patients were selected of which 35 were female and 21 were male. The patients' mean age was 72.7 with a standard deviation of 7.64. All of whom where probable AD patients according to the NINCDS-ADRDA criteria at stage 1 CDR. The group of HS was made up of 56 control subjects (34 female, 22 male) with a mean age of 72.14 and a standard deviation of 7.2. The CDT was applied in both its command (COM) and copy (COP) experimental conditions. RESULTS: The main psychometric parameters analysed in the studied series showed the following values: internal consistency (Cronbach's alpha coefficient 0.9029); cut off point CT COM 6 with 92.80, sensitivity; false negatives (FN) 7.2 with a specificity rating 93.48; false positive (FP) 6.52 with 93.16 efficacy; cut off point CT COP 8 with 73.11 sensitivity; FN 26.89 with 90.58 specificity; FP 9.42 with 82.49 efficacy. CONCLUSION: The CDT can be used to discriminate between HS and those in the initial stages of AD in the given sample using the established application and scoring criteria.
INTRODUCTION: The Clock Drawing Test (CDT) has been used in recent years as a simple neuropsychological instrument to assess cognitive deterioration associated with dementia, even though uniform operative criteria with respect to its application and scoring have not been established. OBJECTIVE: To present application normatives and establish the most relevant psychometric criteria of the CDT in a sample of healthy subjects (HS) and patients with Alzheimer's disease (AD). PATIENTS AND METHODS: 56 patients were selected of which 35 were female and 21 were male. The patients' mean age was 72.7 with a standard deviation of 7.64. All of whom where probable ADpatients according to the NINCDS-ADRDA criteria at stage 1 CDR. The group of HS was made up of 56 control subjects (34 female, 22 male) with a mean age of 72.14 and a standard deviation of 7.2. The CDT was applied in both its command (COM) and copy (COP) experimental conditions. RESULTS: The main psychometric parameters analysed in the studied series showed the following values: internal consistency (Cronbach's alpha coefficient 0.9029); cut off point CT COM 6 with 92.80, sensitivity; false negatives (FN) 7.2 with a specificity rating 93.48; false positive (FP) 6.52 with 93.16 efficacy; cut off point CT COP 8 with 73.11 sensitivity; FN 26.89 with 90.58 specificity; FP 9.42 with 82.49 efficacy. CONCLUSION: The CDT can be used to discriminate between HS and those in the initial stages of AD in the given sample using the established application and scoring criteria.
Authors: Javier Olazarán; Meritxell Valentí; Belén Frades; María Ascensión Zea-Sevilla; Marina Ávila-Villanueva; Miguel Ángel Fernández-Blázquez; Miguel Calero; José Luis Dobato; Juan Antonio Hernández-Tamames; Beatriz León-Salas; Luis Agüera-Ortiz; Jorge López-Álvarez; Pedro Larrañaga; Concha Bielza; Juan Álvarez-Linera; Pablo Martínez-Martín Journal: Front Aging Neurosci Date: 2015-09-30 Impact factor: 5.750
Authors: José I Recio-Rodríguez; Cristina Lugones-Sanchez; Cristina Agudo-Conde; Jesús González-Sánchez; Olaya Tamayo-Morales; Susana Gonzalez-Sanchez; Carmen Fernandez-Alonso; Jose A Maderuelo-Fernandez; Sara Mora-Simon; Manuel A Gómez-Marcos; Emiliano Rodriguez-Sanchez; Luis Garcia-Ortiz Journal: BMC Geriatr Date: 2019-01-23 Impact factor: 3.921
Authors: Juliana Vergel Hernández; María Eugenia Barrera Robledo; Carlos Alberto Hurtado González; Carlos Steven Marmolejo Escobar; Sebastián Ospina Otalvaro; Juan David Sánchez Tobón; Pablo Miguel Arango de la Pava; Juan José Alvarez Journal: Case Rep Neurol Date: 2021-07-08