BACKGROUND AND OBJECTIVES: This study was undertaken to study the behavior of superficial soft tissue sarcomas (STS) and determine the factors related to prognosis. METHODS: The clinical records of 105 adults (56 men, 49 women, mean age: 56.4 years) were retrospectively analyzed. Univariate analysis was performed on the entire group for overall survival (OS), and metastasis-free survival (MFS). Local recurrence-free survival (LRFS) was studied only on patients first treated in our institute. RESULTS: With a median follow-up of 111.9 months, 66 (62.9%) patients were alive; 25 (23.8%) had died of their disease. For the entire series, 10-year OS and MFS were 62.5% and 71.9% respectively. For fifty-two patients treated for their sarcoma at the Institution since the first tumor occurrence event, 10-year LRFS was 80%. Tumor grade was the only factor correlated with OS and MFS, while tumor size was the main factor correlated with LRFS. CONCLUSION: Tumor size affects local control in STS while tumor grade is correlated with OS and MFS.
BACKGROUND AND OBJECTIVES: This study was undertaken to study the behavior of superficial soft tissue sarcomas (STS) and determine the factors related to prognosis. METHODS: The clinical records of 105 adults (56 men, 49 women, mean age: 56.4 years) were retrospectively analyzed. Univariate analysis was performed on the entire group for overall survival (OS), and metastasis-free survival (MFS). Local recurrence-free survival (LRFS) was studied only on patients first treated in our institute. RESULTS: With a median follow-up of 111.9 months, 66 (62.9%) patients were alive; 25 (23.8%) had died of their disease. For the entire series, 10-year OS and MFS were 62.5% and 71.9% respectively. For fifty-two patients treated for their sarcoma at the Institution since the first tumor occurrence event, 10-year LRFS was 80%. Tumor grade was the only factor correlated with OS and MFS, while tumor size was the main factor correlated with LRFS. CONCLUSION:Tumor size affects local control in STS while tumor grade is correlated with OS and MFS.
Authors: Robert W Gordon; Sree Harsha Tirumani; Vikram Kurra; Atul B Shinagare; Jyothi P Jagannathan; Jason L Hornick; Nikhil H Ramaiya Journal: Skeletal Radiol Date: 2014-02-05 Impact factor: 2.199
Authors: William C Eward; Alexander L Lazarides; Anthony M Griffin; Patrick W O'Donnell; Amir Sternheim; Anne O'Neill; Stefan O Hofer; Peter C Ferguson; Jay S Wunder Journal: Plast Reconstr Surg Glob Open Date: 2017-11-13
Authors: Armanda De Marchi; Simona Pozza; Lorena Charrier; Filadelfo Cannone; Franco Cavallo; Alessandra Linari; Raimondo Piana; Irene Geniò; Paolo Balocco; Alessandro Massè Journal: Int J Environ Res Public Health Date: 2020-11-28 Impact factor: 3.390
Authors: Valerie Francescutti; Sartaj S Sanghera; Richard T Cheney; Austin Miller; Kilian Salerno; Rachel Burke; Joseph J Skitzki; John M Kane Journal: Sarcoma Date: 2015-11-08