Literature DB >> 10361694

Construction and characterization of Escherichia coli disruptants defective in the yaeM gene.

T Kuzuyama1, S Takahashi, H Seto.   

Abstract

Escherichia coli disruptants defective in the yaeM gene, which is located at 4.2 min on the chromosome map, were constructed and characterized. The disruptants showed auxotrophy for 2-C-methylerythritol, a free alcohol of 2-C-methyl-D-erythritol 4-phosphate that is a biosynthetic precursor in the nonmevalonate pathway. This result clearly shows that the yaeM gene is indeed involved in this pathway in E. coli.

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Year:  1999        PMID： 10361694     DOI： 10.1271/bbb.63.776

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  15 in total

1.  Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.

Authors:  Jooyoung Park; Ann M Guggisberg; Audrey R Odom; Niraj H Tolia
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2015-08-25

Review 2.  The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target.

Authors:  Hyungjin Eoh; Patrick J Brennan; Dean C Crick
Journal:  Tuberculosis (Edinb)       Date:  2008-09-14       Impact factor: 3.131

3.  Isoprenoid metabolism in apicomplexan parasites.

Authors:  Leah Imlay; Audrey R Odom
Journal:  Curr Clin Microbiol Rep       Date:  2014-12-01

4.  Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr).

Authors:  Christopher M Armstrong; David J Meyers; Leah S Imlay; Caren Freel Meyers; Audrey R Odom
Journal:  Antimicrob Agents Chemother       Date:  2015-06-29       Impact factor: 5.191

5.  A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190.

Authors:  M Takagi; T Kuzuyama; S Takahashi; H Seto
Journal:  J Bacteriol       Date:  2000-08       Impact factor: 3.490

6.  A cytosolic Arabidopsis D-xylulose kinase catalyzes the phosphorylation of 1-deoxy-D-xylulose into a precursor of the plastidial isoprenoid pathway.

Authors:  Andréa Hemmerlin; Denis Tritsch; Michael Hartmann; Karine Pacaud; Jean-François Hoeffler; Alain van Dorsselaer; Michel Rohmer; Thomas J Bach
Journal:  Plant Physiol       Date:  2006-08-18       Impact factor: 8.340

7.  Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster.

Authors:  Takashi Kawasaki; Yutaka Hayashi; Tomohisa Kuzuyama; Kazuo Furihata; Nobuya Itoh; Haruo Seto; Tohru Dairi
Journal:  J Bacteriol       Date:  2006-02       Impact factor: 3.490

8.  Evidence of a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis.

Authors:  F X Cunningham; T P Lafond; E Gantt
Journal:  J Bacteriol       Date:  2000-10       Impact factor: 3.490

9.  A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.

Authors:  Baichen Zhang; Kristin M Watts; Dana Hodge; Lisa M Kemp; David A Hunstad; Leslie M Hicks; Audrey R Odom
Journal:  Biochemistry       Date:  2011-04-11       Impact factor: 3.162

10.  Functional genetic analysis of the Plasmodium falciparum deoxyxylulose 5-phosphate reductoisomerase gene.

Authors:  Audrey R Odom; Wesley C Van Voorhis
Journal:  Mol Biochem Parasitol       Date:  2009-12-16       Impact factor: 1.759
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