Literature DB >> 10360739

Acyl-CoA: cholesterol acyltransferase inhibitory activity of ginseng sapogenins, produced from the ginseng saponins.

B M Kwon1, M K Kim, N I Baek, D S Kim, J D Park, Y K Kim, H K Lee, S I Kim.   

Abstract

Ginseng sapogenins were produced from ginseng saponins, isolated from Korean ginseng roots. Ginseng saponins very mildly inhibited acyl-CoA:cholesterol acyltransferase (ACAT) in vitro, however, the sapogenins showed strong inhibitory activity on microsomal ACAT. Therefore, the sapogenins will be one of key ingredients of ginseng affected a lowering of the serum total cholesterol level.

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Year:  1999        PMID: 10360739     DOI: 10.1016/s0960-894x(99)00208-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Protective effect of Panax ginseng against serum biochemical changes and apoptosis in kidney of rats treated with gentamicin sulphate.

Authors:  Yildiray Kalkan; Kubra Asena Terim Kapakin; Adem Kara; Tennur Atabay; Ali Karadeniz; Nejdet Simsek; Emre Karakus; Ismail Can; Serap Yildirim; Seckin Ozkanlar; Emin Sengul
Journal:  J Mol Histol       Date:  2012-04-10       Impact factor: 2.611

  1 in total

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