Literature DB >> 10360733

A highly stereoselective synthesis of plaunotol and its thiourea derivatives as potent antibacterial agents against Helicobacter pylori.

H Kogen1, K Tago, M Arai, E Minami, K Masuda, T Akiyama.   

Abstract

Practical and highly stereoselective synthesis of diterpene alcohol, plaunotol (1) and its thiourea derivatives 2a, 3a and 4a, via Z-selective Wittig reaction between alpha-acetal ketone 5 and phosphonium salt 6 and their antibacterial activity against Helicobacter pylori are described.

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Year:  1999        PMID: 10360733     DOI: 10.1016/s0960-894x(99)00203-6

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Synthesis, urease inhibition, antioxidant, antibacterial, and molecular docking studies of 1,3,4-oxadiazole derivatives.

Authors:  Muhammad Hanif; Khurram Shoaib; Muhammad Saleem; Nasim Hasan Rama; Sumera Zaib; Jamshed Iqbal
Journal:  ISRN Pharmacol       Date:  2012-08-13
  1 in total

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