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Literature DB >> 10358935

Phospholipase D structure and regulation.

Abstract

The recent identification of cDNA clones for phospholipase D has opened the door to new types of investigations into its structure and regulation. PLD activity has been found to be encoded by at least two different genes that contain catalytic domains that relate their mechanism of action to phosphodiesterases. In vivo roles for PLD suggest that it may be important for multiples steps in regulated secretion and membrane biogenesis.

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Year: 1999 PMID： 10358935 DOI： 10.1016/s0009-3084(99)00025-0

Source DB: PubMed Journal: Chem Phys Lipids ISSN： 0009-3084 Impact factor: 3.329

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Cited

25 in total

1. Cell-permeable ceramides preferentially inhibit coated vesicle formation and exocytosis in Chinese hamster ovary compared with Madin-Darby canine kidney cells by preventing the membrane association of ADP-ribosylation factor.

Authors: Abdelkarim Abousalham; Tom C Hobman; Jay Dewald; Michael Garbutt; David N Brindley
Journal: Biochem J Date: 2002-02-01 Impact factor: 3.857

2. Expression of MARCKS effector domain mutants alters phospholipase D activity and cytoskeletal morphology of SK-N-MC neuroblastoma cells.

Authors: Sherry C Morash; Donna Douglas; Christopher R McMaster; Harold W Cook; David M Byers
Journal: Neurochem Res Date: 2005-11 Impact factor: 3.996

Review 3. The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).

Authors: Julian Gomez-Cambronero
Journal: Cell Signal Date: 2011-06-29 Impact factor: 4.315

4. Dual requirement for rho and protein kinase C in direct activation of phospholipase D1 through G protein-coupled receptor signaling.

Authors: G Du; Y M Altshuller; Y Kim; J M Han; S H Ryu; A J Morris; M A Frohman
Journal: Mol Biol Cell Date: 2000-12 Impact factor: 4.138

5. Phospholipase D2 mediates acute aldosterone secretion in response to angiotensin II in adrenal glomerulosa cells.

Authors: Haixia Qin; Michael A Frohman; Wendy B Bollag
Journal: Endocrinology Date: 2010-03-10 Impact factor: 4.736

6. Insulin-stimulated plasma membrane fusion of Glut4 glucose transporter-containing vesicles is regulated by phospholipase D1.

Authors: Ping Huang; Yelena M Altshuller; June Chunqiu Hou; Jeffrey E Pessin; Michael A Frohman
Journal: Mol Biol Cell Date: 2005-03-16 Impact factor: 4.138

Phospholipase D structure and regulation.

1. Cell-permeable ceramides preferentially inhibit coated vesicle formation and exocytosis in Chinese hamster ovary compared with Madin-Darby canine kidney cells by preventing the membrane association of ADP-ribosylation factor.

2. Expression of MARCKS effector domain mutants alters phospholipase D activity and cytoskeletal morphology of SK-N-MC neuroblastoma cells.

Review 3. The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).

4. Dual requirement for rho and protein kinase C in direct activation of phospholipase D1 through G protein-coupled receptor signaling.

5. Phospholipase D2 mediates acute aldosterone secretion in response to angiotensin II in adrenal glomerulosa cells.

6. Insulin-stimulated plasma membrane fusion of Glut4 glucose transporter-containing vesicles is regulated by phospholipase D1.

7. Phospholipase D1b and D2a generate structurally identical phosphatidic acid species in mammalian cells.

Review 8. Phospholipase D/phosphatidic acid signal transduction: role and physiological significance in lung.

9. The expression and cellular localization of phospholipase D isozymes in the developing mouse testis.

10. The role of phospholipase D in osteoblast response to titanium surface microstructure.