| Literature DB >> 10354170 |
A Darvay1, T Basarab, J M McGregor, R Russell-Jones.
Abstract
Although pellagra is a recognized complication of isoniazid therapy, the diagnosis may be overlooked or delayed--sometimes with life-threatening consequences. We report a case of isoniazid-induced pellagra which occurred despite pyridoxine supplementation. Drug withdrawal and supplementation with niacin led to a rapid and sustained clinical improvement. The possible mechanisms of isoniazid induced pellagra are discussed.Entities:
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Year: 1999 PMID： 10354170 DOI： 10.1046/j.1365-2230.1999.00444.x
Source DB: PubMed Journal: Clin Exp Dermatol ISSN： 0307-6938 Impact factor: 3.470