Literature DB >> 10352387

Endometrial development was improved by transdermal estradiol in patients treated with clomiphene citrate.

K Shimoya1, T Tomiyama, K Hashimoto, A Moriyama, A Kawamoto, Y Tokugawa, K Ohashi, F Saji, Y Murata.   

Abstract

The objective of this study was to examine the effect of transdermal estrogen therapy on the endometrial thickness and serum hormone levels in anovulatory patients treated with clomiphene citrate (CC). There was a significant difference in endometrial thickness between the CC + transdermal estrogen group and the CC only group from day -2 to day +2. Serum estradiol (E2) levels in the CC + transdermal estrogen group were significantly higher than those in the CC only group on day -2 and day 0. Our results support that addition of transdermal E2 to the treatment protocol of the women treated with CC elicited a favorable response of the endometrium.

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Year:  1999        PMID: 10352387     DOI: 10.1159/000010116

Source DB:  PubMed          Journal:  Gynecol Obstet Invest        ISSN: 0378-7346            Impact factor:   2.031


  6 in total

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Authors:  Mohamed F M Mitwally; Robert F Casper; Michael P Diamond
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2.  Clinical outcomes of three- or five-day treatment with clomiphene citrate combined with gonadotropins and a timed intercourse cycle in polycystic ovary syndrome patients.

Authors:  Sung-Ah Bae; Jong-Kil Joo; Jong-Ryeol Choi; Sun-Suk Kim; Kyu-Sup Lee
Journal:  Clin Exp Reprod Med       Date:  2015-09-30

Review 3.  Is ovulation induction still a therapeutic problem in patients with polycystic ovary syndrome?

Authors:  S Palomba; F Orio; T Russo; A Falbo; T Cascella; A Colao; G Lombardi; F Zullo
Journal:  J Endocrinol Invest       Date:  2004-09       Impact factor: 4.256

4.  Defining the proliferative phase endometrial defect.

Authors:  Jason G Bromer; Tamir S Aldad; Hugh S Taylor
Journal:  Fertil Steril       Date:  2008-03-07       Impact factor: 7.329

5.  Effects of clomiphene citrate plus estradiol or progesterone on endometrial ultrastructure: An RCT.

Authors:  Robabeh Taheripanah; Maryam Kabir-Salmani; Masoomeh Favayedi; Marzieh Zamaniyan; Narges Malih; Anahita Taheripanah
Journal:  Int J Reprod Biomed       Date:  2020-03-29

6.  A pilot study to prevent a thin endometrium in patients undergoing clomiphene citrate treatment.

Authors:  Akihisa Takasaki; Hiroshi Tamura; Toshiaki Taketani; Katsunori Shimamura; Hitoshi Morioka; Norihiro Sugino
Journal:  J Ovarian Res       Date:  2013-12-27       Impact factor: 4.234

  6 in total

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