Literature DB >> 10351141

Intravenous immunoglobulin and anti-D in idiopathic thrombocytopenic purpura (ITP): mechanisms of action.

A H Lazarus1, J Freedman, J W Semple.   

Abstract

Infusion of large amounts of intravenous immunoglobulin (IVIG) or anti-D can reverse the low platelet count in patients with ITP within hours of the initiation of treatment. In some cases, the effects of IVIG appear to far outlast several half-lives of the product. Several mechanisms have been proposed to explain these rapid and long term effects and these will be discussed in this review.

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Year:  1998        PMID： 10351141     DOI： 10.1016/s0955-3886(98)00043-5

Source DB:  PubMed          Journal:  Transfus Sci        ISSN： 0955-3886


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