Literature DB >> 10350365

Evaluation of the gastric antiulcer activity of fixed oil of Ocimum sanctum (Holy Basil).

S Singh1, D K Majumdar.   

Abstract

The fixed oil of Ocimum sanctum L. (Labiatae) was found to possess significant antiulcer activity against aspirin-, indomethacin-, alcohol-, histamine-, reserpine-, serotonin- and stress-induced ulceration in experimental animal models. Significant inhibition was also observed in gastric secretion and aspirin-induced gastric ulceration in pylorus ligated rats. The lipoxygenase inhibitory, histamine antagonistic and antisecretory effects of the oil could probably have contributed towards antiulcer activity. O. sanctum fixed oil may be considered to be a drug of natural origin which possesses both anti-inflammatory and antiulcer activity.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10350365     DOI： 10.1016/s0378-8741(98)00142-1

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  11 in total

1.  Neuroprotective effects of hydroalcoholic extract of Ocimum sanctum against H2O2 induced neuronal cell damage in SH-SY5Y cells via its antioxidative defence mechanism.

Authors:  M P Venuprasad; Kandikattu Hemanth Kumar; Farhath Khanum
Journal:  Neurochem Res       Date:  2013-08-31       Impact factor: 3.996

2.  Evaluation of antiulcer and antisecretory potential of Linum usitatissimum fixed oil and possible mechanism of action.

Authors:  Gaurav Kaithwas; Dipak K Majumdar
Journal:  Inflammopharmacology       Date:  2010-04-20       Impact factor: 4.473

3.  Ethnomedicinal plants used by traditional healers in Phatthalung Province, Peninsular Thailand.

Authors:  Katesarin Maneenoon; Chuanchom Khuniad; Yaowalak Teanuan; Nisachon Saedan; Supatra Prom-In; Nitiphol Rukleng; Watid Kongpool; Phongsura Pinsook; Winyu Wongwiwat
Journal:  J Ethnobiol Ethnomed       Date:  2015-05-30       Impact factor: 2.733

4.  Assessment of some Herbal Drugs for Prophylaxis of Peptic Ulcer.

Authors:  Ahmed A Gohar; Ahmed A Zaki
Journal:  Iran J Pharm Res       Date:  2014       Impact factor: 1.696

Review 5.  Tulsi - Ocimum sanctum: A herb for all reasons.

Authors:  Marc Maurice Cohen
Journal:  J Ayurveda Integr Med       Date:  2014 Oct-Dec

6.  Evaluation of holy basil mouthwash as an adjunctive plaque control agent in a four day plaque regrowth model.

Authors:  Manasa Hosamane; Anirudh B Acharya; Chhavi Vij; Dhiraj Trivedi; Swati B Setty; Srinath L Thakur
Journal:  J Clin Exp Dent       Date:  2014-12-01

Review 7.  Plants against Helicobacter pylori to combat resistance: An ethnopharmacological review.

Authors:  Doha Abou Baker
Journal:  Biotechnol Rep (Amst)       Date:  2020-05-21

Review 8.  A review on antiulcer activity of few Indian medicinal plants.

Authors:  G Vimala; F Gricilda Shoba
Journal:  Int J Microbiol       Date:  2014-05-25

9.  Chromatographic Profiling of Ellagic Acid in Woodfordia fruticosa Flowers and their Gastroprotective Potential in Ethanol-induced Ulcers in Rats.

Authors:  Yousuf Hussain Syed; Mohib Khan
Journal:  Pharmacognosy Res       Date:  2016-03

10.  Efficacy and safety of Syferol-IHP for the treatment of peptic ulcer disease: a pilot, double-blind randomized trial.

Authors:  George Uchenna Eleje; Henrietta Aritetsoma Ogbunugafor; Chiemelu Dickson Emegoakor; Ebere Innocent Okoye; Ogochukwu Ifeanyi Ezejiofor; Shirley Nneka Chukwurah; Joseph Ifeanyichukwu Ikechebelu; Godwin W Nchinda; Chidozie Godwin Ugochukwu; Lucy Ijeoma Nnaji-Ihedinmah; Festus Basden C Okoye; Frank Uchenna Eneh; Michael Emeka Onwukamuche; Charles Okechukwu Esimone
Journal:  Clin Exp Gastroenterol       Date:  2019-01-15
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.