Successful treatment of porokeratosis with 585 nm pulsed dye laser irradiation.

Porokeratosis, a keratinization and fibroblast cutaneous disorder, is a progressive disease with limited treatment options. We describe a case of linear porokeratosis that responded favorably to a series of 585 nm pulsed dye laser treatments. In addition to its vascular specificity, the pulsed dye laser presumably produces a direct effect on collagen, as well as an indirect effect on histamine and mast cells that could account for the clinical changes seen in our patient.