OBJECTIVES: Somatosensory evoked potential (SEP) studies suggested that some early cortical SEP components may be generated in the primary motor cortex (M1) rather than the primary somatosensory cortex (S1). METHODS: We now used functional magnetic resonance imaging (fMRI) to study activation of S1 and M1 by electrical median nerve stimulation in healthy volunteers. RESULTS: The hand areas of both S1 and M1 showed significant activation (correlation coefficients >0.45) in 7 of 9 subjects (activated volume S1 > M1). For comparison, a sequential finger opposition task significantly activated S1 in 7 and M1 in all 9 subjects (activated volume M1 > S1). CONCLUSIONS: These data show that the electrical stimuli used for SEP recording lead to a functional activation of S1 as well as M1.
OBJECTIVES: Somatosensory evoked potential (SEP) studies suggested that some early cortical SEP components may be generated in the primary motor cortex (M1) rather than the primary somatosensory cortex (S1). METHODS: We now used functional magnetic resonance imaging (fMRI) to study activation of S1 and M1 by electrical median nerve stimulation in healthy volunteers. RESULTS: The hand areas of both S1 and M1 showed significant activation (correlation coefficients >0.45) in 7 of 9 subjects (activated volume S1 > M1). For comparison, a sequential finger opposition task significantly activated S1 in 7 and M1 in all 9 subjects (activated volume M1 > S1). CONCLUSIONS: These data show that the electrical stimuli used for SEP recording lead to a functional activation of S1 as well as M1.
Authors: Thomas G Gasser; Erol I Sandalcioglu; Helmut Wiedemayer; Volker Hans; Elke Gizewski; Michael Forsting; Dietmar Stolke Journal: Neurosurg Rev Date: 2003-12-23 Impact factor: 3.042
Authors: Maria Angela Franceschini; Sergio Fantini; John H Thompson; Joseph P Culver; David A Boas Journal: Psychophysiology Date: 2003-07 Impact factor: 4.016
Authors: Teresa J Kimberley; Scott M Lewis; Edward J Auerbach; Lisa L Dorsey; Jeanne M Lojovich; James R Carey Journal: Exp Brain Res Date: 2003-11-15 Impact factor: 1.972
Authors: Ming-Xiong Huang; Roland R Lee; Kathleen M Gaa; Tao Song; Deborah L Harrington; Cathy Loh; Rebecca J Theilmann; J Christopher Edgar; Gregory A Miller; Jose M Canive; Eric Granholm Journal: Brain Topogr Date: 2009-11-27 Impact factor: 3.020