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Literature DB >> 103464

Development of Dickie's small eye, a mutation in the house mouse.

Abstract

A new semidominant mutation in the laboratory mouse, Dickie's small eye (Dey), is described. It is localized on chromosome 2. Heterozygotes show reduced body size, small eyes with coloboma, small or lacking lens with cataract, abnormal folding of the retina and reduction of the pigment layer. The anterior chamber is usually missing. Homozygotes apparently die early in pregnancy.

Entities: Disease Gene Species

Mesh：

Year: 1978 PMID： 103464 DOI： 10.1007/bf00315732

Source DB: PubMed Journal: Anat Embryol (Berl) ISSN： 0340-2061

1 in total

1. A new allele of ocular retardation: early development and morphogenetic cell death.

Authors: K Theiler; D S Varnum; J H Nadeau; L C Stevens; B Cagianut
Journal: Anat Embryol (Berl) Date: 1976-12-22

1 in total

17 in total

Review 1. Mouse chromosome 2.

Authors: L D Siracusa; C M Abbott
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

2. Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients.

Authors: Takuya Nakayama; Marilyn Fisher; Keisuke Nakajima; Akinleye O Odeleye; Keith B Zimmerman; Margaret B Fish; Yoshio Yaoita; Jena L Chojnowski; James D Lauderdale; Peter A Netland; Robert M Grainger
Journal: Dev Biol Date: 2015-02-25 Impact factor: 3.582

Review 3. Mouse chromosome 2.

Authors: L D Siracusa; C M Abbott
Journal: Mamm Genome Date: 1991 Impact factor: 2.957

4. Role of Olf-1 and Pax-6 transcription factors in neurodevelopment.

Authors: J A Davis; R R Reed
Journal: J Neurosci Date: 1996-08-15 Impact factor: 6.167

5. Pax6 expressed in osteocytes inhibits canonical Wnt signaling.

Authors: Ajita Jami; Jogeswar Gadi; Min Jung Lee; Eun Jin Kim; Mi Jeong Lee; Han-Sung Jung; Hong-Hee Kim; Sung-Kil Lim
Journal: Mol Cells Date: 2013-03-22 Impact factor: 5.034

6. Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation.

Authors: Tessa Walcher; Qing Xie; Jian Sun; Martin Irmler; Johannes Beckers; Timucin Öztürk; Dierk Niessing; Anastassia Stoykova; Ales Cvekl; Jovica Ninkovic; Magdalena Götz
Journal: Development Date: 2013-03 Impact factor: 6.868

Development of Dickie's small eye, a mutation in the house mouse.

1. A new allele of ocular retardation: early development and morphogenetic cell death.

Review 1. Mouse chromosome 2.

2. Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients.

Review 3. Mouse chromosome 2.

4. Role of Olf-1 and Pax-6 transcription factors in neurodevelopment.

5. Pax6 expressed in osteocytes inhibits canonical Wnt signaling.

6. Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation.

7. Development of coloboma (Cm/+), a mutation with anterior lens adhesion.

8. Morphometric study of the optic nerve of adult normal mice and mice heterozygous for the Small eye mutation (Sey/+).

9. Relationship of Pax6 activity levels to the extent of eye development in the mouse, Mus musculus.

10. Craniofacial abnormalities in homozygous Small eye (Sey/Sey) embryos and newborn mice.