Literature DB >> 10344903

Mega-mergers in the pharmaceutical industry. In whose interests?

A L Po1.   

Abstract

Companies merge to achieve economies of scale. In an industry such as the pharmaceutical industry which relies on a high level of investment in research and development, such mergers appear rational. However, it is not at all obvious that a higher level of investment by a smaller number of firms will necessarily lead to an increased rate of genuine innovations. There is a risk that conflicts of interest and the pursuit of short term gains may encourage more mergers than is optimal for the industry. The impact of mega-mergers in the pharmaceutical industry on research output, employees, shareholders, financial advisers, managers and patients is discussed. A healthy pharmaceutical industry, able to invest the necessary resources in the development of innovative medicines is in the interest of patients and shareholders alike. Over-concentration may interfere with innovative activity and lead to monopolistic power. Close scrutiny of merger activity is important but in a deregulated world, governments may have little power to act. In any case, a drug-specific monopolistic industry may be beneficial to some countries which may therefore be reluctant to act in the interest of the world as a single community in search of more effective medicines.

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Year:  1998        PMID: 10344903     DOI: 10.2165/00019053-199814040-00002

Source DB:  PubMed          Journal:  Pharmacoeconomics        ISSN: 1170-7690            Impact factor:   4.981


  10 in total

1.  The new drug approvals of 1993, 1994, and 1995: trends in drug development.

Authors:  K I Kaitin; M Manocchia
Journal:  Am J Ther       Date:  1997-01       Impact factor: 2.688

2.  A closer look at the returns and risk of pharmaceutical R&D.

Authors:  P Joglekar; M L Paterson
Journal:  J Health Econ       Date:  1986-06       Impact factor: 3.883

Review 3.  Returns to R&D on new drug introductions in the 1980s.

Authors:  H G Grabowski; J M Vernon
Journal:  J Health Econ       Date:  1994-12       Impact factor: 3.883

4.  Cost of innovation in the pharmaceutical industry.

Authors:  J A DiMasi; R W Hansen; H G Grabowski; L Lasagna
Journal:  J Health Econ       Date:  1991-07       Impact factor: 3.883

5.  Lessons from international experience in controlling pharmaceutical expenditure. II: Influencing doctors.

Authors:  K Bloor; N Freemantle
Journal:  BMJ       Date:  1996-06-15

6.  Drug company merger should benefit research.

Authors:  G Labreque
Journal:  BMJ       Date:  1998-02-14

7.  Lessons from international experience in controlling pharmaceutical expenditure. I: Influencing patients.

Authors:  N Freemantle; K Bloor
Journal:  BMJ       Date:  1996-06-08

8.  Lessons from international experience in controlling pharmaceutical expenditure. III: Regulating industry.

Authors:  K Bloor; A Maynard; N Freemantle
Journal:  BMJ       Date:  1996-07-06

9.  Too soon to market.

Authors:  T H Dent; S Hawke
Journal:  BMJ       Date:  1997-11-15

10.  Approval of new drugs in the United States. Comparison with the United Kingdom, Germany, and Japan.

Authors:  D A Kessler; A E Hass; K L Feiden; M Lumpkin; R Temple
Journal:  JAMA       Date:  1996-12-11       Impact factor: 56.272

  10 in total

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