Literature DB >> 10340682

Receptor pharmacology of neuroleptics: relation to clinical effects.

E Richelson1.   

Abstract

This article reviews the receptor pharmacology of neuroleptics, with a focus on newer drugs (e.g., risperidone, olanzapine, sertindole, quetiapine, and ziprasidone) in contrast to older compounds. All these newer compounds are considered to be atypical neuroleptics based upon certain criteria, which are reviewed. Several hypotheses about the molecular mechanisms that explain atypicality are considered. Finally, the in vitro receptor binding data presented for these compounds are related to the therapeutic and adverse effects of these drugs.

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Year:  1999        PMID： 10340682

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN： 0160-6689            Impact factor:   4.384


  47 in total

1.  Safety and tolerability: how do newer generation "atypical" antipsychotics compare?

Authors:  Rajiv Tandon
Journal:  Psychiatr Q       Date:  2002

Review 2.  Overdose of atypical antipsychotics: clinical presentation, mechanisms of toxicity and management.

Authors:  Michael Levine; Anne-Michelle Ruha
Journal:  CNS Drugs       Date:  2012-07-01       Impact factor: 5.749

Review 3.  Treatment of the metabolic disturbances caused by antipsychotic drugs: focus on potential drug interactions.

Authors:  Trino Baptista; N M K Ng Ying Kin; Serge Beaulieu
Journal:  Clin Pharmacokinet       Date:  2004       Impact factor: 6.447

Review 4.  Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment.

Authors:  Christine Konradi; Stephan Heckers
Journal:  Pharmacol Ther       Date:  2003-02       Impact factor: 12.310

5.  Best practice guide for the treatment of nightmare disorder in adults.

Authors:  R Nisha Aurora; Rochelle S Zak; Sanford H Auerbach; Kenneth R Casey; Susmita Chowdhuri; Anoop Karippot; Rama K Maganti; Kannan Ramar; David A Kristo; Sabin R Bista; Carin I Lamm; Timothy I Morgenthaler
Journal:  J Clin Sleep Med       Date:  2010-08-15       Impact factor: 4.062

6.  Colitis possibly induced by quetiapine.

Authors:  Renaud de Beaurepaire; Isabelle Trinh; Sophie Guirao; Muriel Taieb
Journal:  BMJ Case Rep       Date:  2015-02-26

Review 7.  Atypical antipsychotics: from potassium channels to torsade de pointes and sudden death.

Authors:  Karine Titier; Pierre-Olivier Girodet; Hélène Verdoux; Mathieu Molimard; Bernard Bégaud; Wilhelm Haverkamp; Malcolm Lader; Nicholas Moore
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

Review 8.  Are second generation antipsychotics a distinct class?

Authors:  Caroline Bonham; Christopher Abbott
Journal:  J Psychiatr Pract       Date:  2008-07       Impact factor: 1.325

9.  Haloperidol and risperidone have specific effects on altered pain sensitivity in the ketamine model of schizophrenia.

Authors:  Axel Becker; Gisela Grecksch; Gerald Zernig; Elisabeth Ladstaetter; Christoph Hiemke; Ulrich Schmitt
Journal:  Psychopharmacology (Berl)       Date:  2008-09-23       Impact factor: 4.530

10.  Treating bipolar disorder in the primary care setting: the role of aripiprazole.

Authors:  J Sloan Manning; Susan L McElroy
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2009
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