| Literature DB >> 10339632 |
Abstract
Plasma concentration of glucose is found within a relatively narrow range of values for most animal species, yet it has little correlation with maximum lifespan; however, hyperglycemia in most animals is associated with premature death. This article presents evidence for hyperglycemia-induced tissue toxicity and discusses potential mechanisms of glucotoxicity and implications for the aging organism.Entities:
Mesh：
Substances：
Year: 1999 PMID： 10339632
Source DB: PubMed Journal: Clin Geriatr Med ISSN： 0749-0690 Impact factor: 3.076