A Panda1, N Pushker, L M Bageshwar. 1. Cornea Service, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
Abstract
PURPOSE: To evaluate the effectiveness of lateral tarsorrhaphy for the management of postkeratoplasty epithelial defects. METHOD: Thirty-six patients with persistent postkeratoplasty epithelial defects that did not heal despite topical medical therapy for a period of 96 hours were treated with either alateral tarsorrhaphy (18 patients) or with tight patching (18 patients). All patients were evaluated daily by slit-lamp examination until complete reepithelialization occurred. RESULTS: The epithelial healing was significantly faster (7.61+/-0.91 days vs. 12.6+/-1.61 days, p<0.5) in the lateral tarsorrhaphy group. Further, the patients with lateral tarsorrhaphies were significantly more comfortable when compared with those of the patching group (p<0.05). CONCLUSION:Lateral tarsorrhaphy provides quick symptomatic relief and faster corneal epithelial defect healing. Therefore, it may be of benefit in cases of postkeratoplasty persistent epithelial defects.
RCT Entities:
PURPOSE: To evaluate the effectiveness of lateral tarsorrhaphy for the management of postkeratoplasty epithelial defects. METHOD: Thirty-six patients with persistent postkeratoplasty epithelial defects that did not heal despite topical medical therapy for a period of 96 hours were treated with either a lateral tarsorrhaphy (18 patients) or with tight patching (18 patients). All patients were evaluated daily by slit-lamp examination until complete reepithelialization occurred. RESULTS: The epithelial healing was significantly faster (7.61+/-0.91 days vs. 12.6+/-1.61 days, p<0.5) in the lateral tarsorrhaphy group. Further, the patients with lateral tarsorrhaphies were significantly more comfortable when compared with those of the patching group (p<0.05). CONCLUSION: Lateral tarsorrhaphy provides quick symptomatic relief and faster corneal epithelial defect healing. Therefore, it may be of benefit in cases of postkeratoplasty persistent epithelial defects.
Authors: R B Vajpayee; N Mukerji; R Tandon; N Sharma; R M Pandey; N R Biswas; N Malhotra; S A Melki Journal: Br J Ophthalmol Date: 2003-11 Impact factor: 4.638