Literature DB >> 1033456

Mechanism of action of methotrexate. IV. Free intracellular methotrexate required to suppress dihydrofolate reduction to tetrahydrofolate by Ehrlich ascites tumor cells in vitro.

J C White, I D Goldman.   

Abstract

Entities:  

Mesh:

Substances:

Year:  1976        PMID: 1033456

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN: 0026-895X            Impact factor:   4.436


× No keyword cloud information.
  15 in total

1.  Dose-dependent pharmacokinetics of the aldose reductase inhibitor imirestat in man.

Authors:  R K Brazzell; P R Mayer; R Dobbs; P J McNamara; R L Teng; J T Slattery
Journal:  Pharm Res       Date:  1991-01       Impact factor: 4.200

2.  Use of the circuit simulation program SPICE2 for analysis of the metabolism of anticancer drugs.

Authors:  J C White
Journal:  Bull Math Biol       Date:  1986       Impact factor: 1.758

3.  Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model.

Authors:  Rakesh K Singh; Leon van Haandel; Paul Kiptoo; Mara L Becker; Teruna J Siahaan; Ryan S Funk
Journal:  Eur J Pharmacol       Date:  2019-04-02       Impact factor: 4.432

4.  5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates.

Authors:  D J Fernandes; J R Bertino
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

5.  The interaction between fluoropyrimidines and methotrexate, and [4C]-formate incorporation into nucleic acids and protein.

Authors:  D Bowen; E Fölsch; L A Guernsey
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

6.  Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates.

Authors:  Adam L VanWert; Douglas H Sweet
Journal:  Pharm Res       Date:  2007-07-28       Impact factor: 4.200

7.  Methotrexate polyglutamate synthesis by cultured human breast cancer cells.

Authors:  R L Schilsky; B D Bailey; B A Chabner
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205

8.  Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide.

Authors:  J E Baggott; W H Vaughn; B B Hudson
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857

Review 9.  Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs?

Authors:  Vasco Crispim Romão; Helena Canhão; João Eurico Fonseca
Journal:  BMC Med       Date:  2013-01-23       Impact factor: 8.775

10.  Protection of cells from methotrexate toxicity by 7-hydroxymethotrexate.

Authors:  J M Gaukroger; L Wilson
Journal:  Br J Cancer       Date:  1984-09       Impact factor: 7.640

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.