Literature DB >> 10333343

Clinical presentation and management of patients with uncontrolled, severe hypertension: results from a public teaching hospital.

R A Preston1, N M Baltodano, J Cienki, B J Materson.   

Abstract

CONTEXT: There is relatively little data available on the management of patients with severe, uncomplicated hypertension and severe hypertension with stable hypertensive complications.
OBJECTIVE: To determine the incidence, clinical features, acute management, and clinical course of severe, uncomplicated hypertension and severe hypertension with stable hypertensive complications presenting for emergency department care in a large public teaching hospital.
DESIGN: Chart survey of consecutive emergency department visits. PATIENTS: Ninety-one of 2898 consecutive visits to a public teaching hospital emergency department were specifically for severe, uncomplicated hypertension.
RESULTS: Of 2898 consecutive medical emergency department visits, there were 142 (4.9%) patient visits specifically for systolic blood pressure (SBP) > or =220 mm Hg or diastolic blood pressure (DBP) > or =120 mm Hg. Ninety-one of the 142 patient visits were for severe hypertension in the absence of acute target organ impact or neuroretinopathy. Eighty-nine patients received acute drug therapy. Twenty-nine patients received two drugs, and 15 received three drugs. Sixty-eight patients (75%) received clonidine, and 15 (16.5%) received short-acting nifedipine despite widely published concerns about the safety of this practice. We found a wide variability of blood pressure response to treatment. The average decline in SBP was 50+/-31 mm Hg and the average decline of DBP was 34+/-20 mm Hg over 4.2+/-2.9 h. Forty-two patients (46%) had the SBP reduced to less than 160 mm Hg, and 46 patients (50%) the DBP to less than 100 mm Hg. Long-term management and follow-up were suboptimal. Of 74 patients discharged from the emergency room, 22 patients (30%) returned because of uncontrolled hypertension within an average of 33+/-28 days, 10 patients with hypertensive complications.
CONCLUSIONS: Severe hypertension continues to present an important and common problem. Physicians appear to place a strong emphasis on acute lowering of the blood pressure to near-normal levels. Patients are frequently lost to follow-up and have a very high rate of recurrent emergency department visits and hypertensive complications. This study points to a need for detailed, specific practice guidelines and comprehensive disease management protocols for severe, uncomplicated hypertension.

Entities:  

Mesh:

Substances:

Year:  1999        PMID: 10333343     DOI: 10.1038/sj.jhh.1000796

Source DB:  PubMed          Journal:  J Hum Hypertens        ISSN: 0950-9240            Impact factor:   3.012


  11 in total

1.  What is urgent about hypertensive urgency?

Authors:  Cian Hackett; Scott Garrison; Michael R Kolber
Journal:  Can Fam Physician       Date:  2017-07       Impact factor: 3.275

2.  Playing a role in secondary prevention in the ED: longitudinal study of patients with asymptomatic elevated blood pressures following a brief education intervention: a pilot study.

Authors:  H M Prendergast; J Colla; M Del Rios; J Marcucci; R Schulz; T O'Neal
Journal:  Public Health       Date:  2015-03-19       Impact factor: 2.427

3.  Risk of Intracerebral Hemorrhage after Emergency Department Discharges for Hypertension.

Authors:  Babak B Navi; Neal S Parikh; Michael P Lerario; Alexander E Merkler; Richard I Lappin; Jahan Fahimi; Costantino Iadecola; Hooman Kamel
Journal:  J Stroke Cerebrovasc Dis       Date:  2016-04-08       Impact factor: 2.136

4.  BP goal achievement in patients with uncontrolled hypertension : results of the treat-to-target post-marketing survey with irbesartan.

Authors:  Joachim Schrader; Peter Bramlage; Stephan Lüders; Martin Thoenes; Andreas Schirmer; Dieter W Paar
Journal:  Clin Drug Investig       Date:  2007       Impact factor: 2.859

Review 5.  Hypertensive crises: emergencies and urgencies.

Authors:  Donald G Vidt
Journal:  J Clin Hypertens (Greenwich)       Date:  2004-09       Impact factor: 3.738

6.  LCZ696, a First-in-Class Angiotensin Receptor-Neprilysin Inhibitor: The First Clinical Experience in Patients With Severe Hypertension.

Authors:  Kazuomi Kario; Yuko Tamaki; Naoko Okino; Hiromi Gotou; Min Zhu; Jack Zhang
Journal:  J Clin Hypertens (Greenwich)       Date:  2015-09-24       Impact factor: 3.738

7.  Efficacy and safety of irbesartan/HCTZ combination therapy as initial treatment for rapid control of severe hypertension.

Authors:  Joel M Neutel; Stanley S Franklin; Suzanne Oparil; Amitabha Bhaumik; Agata Ptaszynska; Pablo Lapuerta
Journal:  J Clin Hypertens (Greenwich)       Date:  2006-12       Impact factor: 3.738

Review 8.  Emerging insights in the first-step use of antihypertensive combination therapy.

Authors:  Keith Norris; Joel M Neutel
Journal:  J Clin Hypertens (Greenwich)       Date:  2007-12       Impact factor: 3.738

Review 9.  The risks and benefits of initial irbesartan/hydrochlorothiazide combination therapy in patients with severe hypertension.

Authors:  Pablo Lapuerta; Stanley Franklin
Journal:  J Clin Hypertens (Greenwich)       Date:  2009-05       Impact factor: 3.738

10.  The epidemiology and management of severe hypertension.

Authors:  A M Borzecki; B Kader; D R Berlowitz
Journal:  J Hum Hypertens       Date:  2010-01       Impact factor: 3.012

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.