Literature DB >> 10333127

Comparison of albumin versus bicarbonate treatment for neonatal metabolic acidosis.

H Dixon1, K Hawkins, T Stephenson.   

Abstract

UNLABELLED: In this study the effectiveness of 4.5% human albumin was compared with 4.2% sodium bicarbonate for neonatal metabolic acidosis, using a randomised controlled trial. The change in median pH following bicarbonate was more than twice that in the albumin group. This was statistically significant.
CONCLUSION: In normotensive infants, use of bicarbonate to correct metabolic acidosis may be more effective than use of albumin.

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Year:  1999        PMID： 10333127     DOI： 10.1007/s004310051104

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  2 in total

Review 1.  Early volume expansion for prevention of morbidity and mortality in very preterm infants.

Authors:  D A Osborn; N Evans
Journal:  Cochrane Database Syst Rev       Date:  2004

Review 2.  Base administration or fluid bolus for preventing morbidity and mortality in preterm infants with metabolic acidosis.

Authors:  C J Lawn; F J Weir; W McGuire
Journal:  Cochrane Database Syst Rev       Date:  2005-04-18
  2 in total

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