| Literature DB >> 10328340 |
S M Healy1, E Wildfang, R A Zakharyan, H V Aposhian.
Abstract
Biotransformation of inorganic arsenic in mammals is catalyzed by three serial enzyme activities: arsenate reductase, arsenite methyltransferase, and monomethylarsonate methyltransferase. Our laboratory has purified and characterized these enzymes in order to understand the mechanisms and elucidate the variations of the responses to arsenate/arsenite challenge. Our results indicate a marked deficiency and diversity of these enzyme activities in various animal species.Entities:
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Year: 1999 PMID： 10328340 DOI： 10.1007/BF02783907
Source DB: PubMed Journal: Biol Trace Elem Res ISSN： 0163-4984 Impact factor: 3.738