| Literature DB >> 10328310 |
J P Beck1, M A Curry, R J Chorvat, L W Fitzgerald, P J Gilligan, R Zaczek, G L Trainor.
Abstract
A series of thiazolo[4,5-d]pyrimidine thiones and -ones was prepared and discovered to have good binding affinity to the CRH-R1 receptor, thus showing promise as a new class of potential anxiolytics and/or antidepressants.Entities:
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Year: 1999 PMID： 10328310 DOI： 10.1016/s0960-894x(99)00159-6
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823