| Literature DB >> 10328306 |
J S Carter1, D J Rogier, M J Graneto, K Seibert, C M Koboldt, Y Zhang, J J Talley.
Abstract
A series of novel sulfone substituted 4,5-diarylthiazoles have been synthesized and evaluated for their inhibition of the two isoforms of human cyclooxygenase (COX-1 and COX-2). This series displays exceptionally selective COX-2 inhibition.Entities:
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Year: 1999 PMID： 10328306 DOI： 10.1016/s0960-894x(99)00158-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823