Literature DB >> 1032662

Dissolution of two-component solids.

S A Shah, E L Parrott.   

Abstract

The dissolution rates of compressed two-component mixtures were investigated. A good correlation between the composition of the solid and its observed dissolution rate was demonstrated by regression analysis. A model for dissolution was applied to compressed mixtures of aspirin-salicylic acid, aspirin-phenacetin, phenacetin-caffeine, and aspirin and caffeine (the last mixture complexes in solution).

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Year:  1976        PMID： 1032662     DOI： 10.1002/jps.2600651223

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  2 in total

1.  A convective-diffusion model for dissolution of two non-interacting drug mixtures from co-compressed slabs under laminar hydrodynamic conditions.

Authors:  S Neervannan; L S Dias; M Z Southard; V J Stella
Journal:  Pharm Res       Date:  1994-09       Impact factor: 4.200

2.  Dependence of dissolution rate on surface area: is a simple linear relationship valid for co-compressed drug mixtures?

Authors:  S Neervannan; M Z Southard; V J Stella
Journal:  Pharm Res       Date:  1994-10       Impact factor: 4.200
  2 in total

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