| Literature DB >> 10325710 |
T Akçay1, D Konukoğlu, Y Dínçer.
Abstract
Urinary glycosaminoglycan (GAG) excretion was measured in children with idiopathic urolithiasis (15 girls and 10 boys; mean (SD) age 6.2 (2.4) years) and in healthy controls (10 girls and 14 boys; mean (SD) age 6.8 (3.8) years). GAG excretion was expressed as a GAG/creatinine (mg/g) ratio and was evaluated using dimethylmethylene blue. In healthy control children, the mean (SD) GAG/creatinine ratio was 31.67 (12.76) and it was similar in girls and boys. The children with idiopathic urolithiasis had significantly lower mean (SD) GAG/creatinine ratios than controls (22.59 (7.35)). Therefore, urinary GAG excretion may be important in the disease process in children with urolithiasis, as it is in adults.Entities:
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Year: 1999 PMID： 10325710 PMCID： PMC1717848 DOI： 10.1136/adc.80.3.271
Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791