Z H Huang1, Y S Dong, W Y Ye. 1. Department of Pediatrics, Tongji Hospital, Tongji Medical University, Wuhan.
Abstract
OBJECTIVE: To evaluate the role of Rhubarb in treating infantile cholestatic hepatitis syndrome (IHS). METHODS: Forty-four patients of the treatment group were treated with Rhubarb per os and/or duodenal infusion, 20 cases of the control group were treated with general liver protecting therapy such as inosine, vitamin C and glucose. Serum bilirubin, alanine transaminase (ALT) and gamma-glutamyl transferase (gamma-GT) level, bilirubin in duodenal juice and liver size were observed before and after treatment. RESULTS: In the treatment group, 18 cases were markedly effective, 21 effective, 3 ineffective and 2 were deteriorated, while in the control group, the respective number were 0, 4, 13 and 3. CONCLUSIONS: Rhubarb was a markedly effective in cholagoging and abating of jaundice, it could promote the recovery of liver function, dredge the cholestasis in cholangiole and micro-cholangiole so as to promote the bile secretion.
OBJECTIVE: To evaluate the role of Rhubarb in treating infantile cholestatic hepatitis syndrome (IHS). METHODS: Forty-four patients of the treatment group were treated with Rhubarb per os and/or duodenal infusion, 20 cases of the control group were treated with general liver protecting therapy such as inosine, vitamin C and glucose. Serum bilirubin, alanine transaminase (ALT) and gamma-glutamyl transferase (gamma-GT) level, bilirubin in duodenal juice and liver size were observed before and after treatment. RESULTS: In the treatment group, 18 cases were markedly effective, 21 effective, 3 ineffective and 2 were deteriorated, while in the control group, the respective number were 0, 4, 13 and 3. CONCLUSIONS:Rhubarb was a markedly effective in cholagoging and abating of jaundice, it could promote the recovery of liver function, dredge the cholestasis in cholangiole and micro-cholangiole so as to promote the bile secretion.