Literature DB >> 10322454

Histone deacetylases: transcriptional repression with SINers and NuRDs.

D E Ayer1.   

Abstract

The DNA in eukaryotic cells is packaged into chromatin, which functions as a boundary to the transcriptional activation process. The nucleosome is the basic repeating unit of chromatin. The purification and characterization of several chromatin-remodelling complexes and the demonstration that histone acetyltransferases and histone deacetylases are regulatory components of coactivator and corepressor complexes, respectively, demonstrates that the nucleosome is not simply a static architectural feature of chromatin but, rather, plays a dynamic and integral role in the regulation of gene expression. This review focuses primarily on histone deacetylases and deacetylase-containing complexes and their role in mediating transcriptional repression.

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Year:  1999        PMID： 10322454     DOI： 10.1016/s0962-8924(99)01536-6

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  85 in total

1.  Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain.

Authors:  E C Forsberg; K M Downs; H M Christensen; H Im; P A Nuzzi; E H Bresnick
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

2.  Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1.

Authors:  S H Yang; E Vickers; A Brehm; T Kouzarides; A D Sharrocks
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

3.  A role for SKIP in EBNA2 activation of CBF1-repressed promoters.

Authors:  S Zhou; M Fujimuro; J J Hsieh; L Chen; S D Hayward
Journal:  J Virol       Date:  2000-02       Impact factor: 5.103

4.  MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network.

Authors:  A N Billin; A L Eilers; K L Coulter; J S Logan; D E Ayer
Journal:  Mol Cell Biol       Date:  2000-12       Impact factor: 4.272

5.  Chromosomal localization links the SIN3-RPD3 complex to the regulation of chromatin condensation, histone acetylation and gene expression.

Authors:  L A Pile; D A Wassarman
Journal:  EMBO J       Date:  2000-11-15       Impact factor: 11.598

6.  The SMRT corepressor is a target of phosphorylation by protein kinase CK2 (casein kinase II).

Authors:  Y Zhou; W Gross; S H Hong; M L Privalsky
Journal:  Mol Cell Biochem       Date:  2001-04       Impact factor: 3.396

7.  The histone deacetylase genes HDA1 and RPD3 play distinct roles in regulation of high-frequency phenotypic switching in Candida albicans.

Authors:  T Srikantha; L Tsai; K Daniels; A J Klar; D R Soll
Journal:  J Bacteriol       Date:  2001-08       Impact factor: 3.490

8.  HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling.

Authors:  T Iso; V Sartorelli; C Poizat; S Iezzi; H Y Wu; G Chung; L Kedes; Y Hamamori
Journal:  Mol Cell Biol       Date:  2001-09       Impact factor: 4.272

9.  The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation.

Authors:  J T Zilfou; W H Hoffman; M Sank; D L George; M Murphy
Journal:  Mol Cell Biol       Date:  2001-06       Impact factor: 4.272

10.  Isotype-restricted corepressor recruitment: a constitutively closed helix 12 conformation in retinoic acid receptors beta and gamma interferes with corepressor recruitment and prevents transcriptional repression.

Authors:  Behnom Farboud; Herborg Hauksdottir; Yun Wu; Martin L Privalsky
Journal:  Mol Cell Biol       Date:  2003-04       Impact factor: 4.272
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