Literature DB >> 10322303

Analysis of B-cell epitopes of the Ro/SS-A autoantigen.

M Wahren-Herlenius1, S Muller, D Isenberg.   

Abstract

Autoantibodies to the Ro and La ribonucleoprotein antigens are found in several rheumatoid diseases. The important epitopes have been studied using synthetic peptides and recombinant antigens to understand how they arise and their implication in disease. Here, we analyse the results of epitope mapping studies of Ro60 and Ro52 autoantigens and focus on the major findings to date.

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Year:  1999        PMID： 10322303     DOI： 10.1016/s0167-5699(99)01458-9

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  17 in total

1.  Sjögren's syndrome associated with systemic lupus erythematosus.

Authors:  Mehmet Taşdemir; Chiar Hasan; Ayşe Ağbaş; Özgür Kasapçopur; Nur Canpolat; Lale Sever; Salim Çalışkan
Journal:  Turk Pediatri Ars       Date:  2016-09-01

2.  Immune response against the coiled coil domain of Sjögren's syndrome associated autoantigen Ro52 induces salivary gland dysfunction.

Authors:  Magdalena Sroka; Harini Bagavant; Indranil Biswas; Abigail Ballard; Umesh S Deshmukh
Journal:  Clin Exp Rheumatol       Date:  2018-01-31       Impact factor: 4.473

3.  Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface.

Authors:  Alexander Espinosa; Janosch Hennig; Aurélie Ambrosi; Madhanagopal Anandapadmanaban; Martina Sandberg Abelius; Yi Sheng; Filippa Nyberg; Cheryl H Arrowsmith; Maria Sunnerhagen; Marie Wahren-Herlenius
Journal:  J Biol Chem       Date:  2011-08-23       Impact factor: 5.157

4.  Extraordinary antigenicity of the human Ro52 autoantigen.

Authors:  Peter D Burbelo; Kathryn H Ching; Brian L Han; Emily R Bush; Westley H Reeves; Michael J Iadarola
Journal:  Am J Transl Res       Date:  2010-03-15       Impact factor: 4.060

Review 5.  Sjögren's syndrome--study of autoantigens and autoantibodies.

Authors:  John G Routsias; Athanasios G Tzioufas
Journal:  Clin Rev Allergy Immunol       Date:  2007-06       Impact factor: 8.667

6.  Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors.

Authors:  Rowan Higgs; Elisa Lazzari; Claire Wynne; Joan Ní Gabhann; Alexander Espinosa; Marie Wahren-Herlenius; Caroline A Jefferies
Journal:  PLoS One       Date:  2010-07-26       Impact factor: 3.240

7.  Different temporal expression of immunodominant Ro60/60 kDa-SSA and La/SSB apotopes.

Authors:  J H Reed; P J Neufing; M W Jackson; R M Clancy; P J Macardle; J P Buyon; T P Gordon
Journal:  Clin Exp Immunol       Date:  2007-04       Impact factor: 4.330

8.  Sensitive and robust luminescent profiling of anti-La and other autoantibodies in Sjogren's syndrome.

Authors:  Peter D Burbelo; Hannah P Leahy; Alexandra T Issa; Sandra Groot; James N Baraniuk; Nikolay P Nikolov; Gabor G Illei; Michael J Iadarola
Journal:  Autoimmunity       Date:  2009-09       Impact factor: 2.815

9.  Clinical, immunological, and immunogenetic aspects of autoantibody production against Ro/SSA, La/SSB and their linear epitopes in primary Sjögren's syndrome (pSS): a European multicentre study.

Authors:  A G Tzioufas; R Wassmuth; U G Dafni; A Guialis; H-J Haga; D A Isenberg; R Jonsson; J R Kalden; H Kiener; C Sakarellos; J S Smolen; N Sutcliffe; C Vitali; E Yiannaki; H M Moutsopoulos
Journal:  Ann Rheum Dis       Date:  2002-05       Impact factor: 19.103

10.  Rapid serological detection of autoantibodies associated with Sjögren's syndrome.

Authors:  Peter D Burbelo; Kathryn H Ching; Alexandra T Issa; Caroline M Loftus; Yi Li; Minoru Satoh; Westley H Reeves; Michael J Iadarola
Journal:  J Transl Med       Date:  2009-09-24       Impact factor: 5.531
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