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Literature DB >> 10322199

Fast forward genetics based on virus-induced gene silencing.

Abstract

Gene expression in plants can be suppressed in a sequence-specific manner by infection with virus vectors carrying fragments of host genes. Recent developments have revealed that the mechanism of this gene silencing is based on an RNA-mediated defence against viruses. It has also emerged that a related mechanism is involved in the post-transcriptional silencing that accounts for between line variation in transgene expression and cosuppresion of transgenes and endogenous genes. The technology of virus-induced gene silencing is being refined and adapted as a high throughput procedure for functional genomics in plants.

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Year: 1999 PMID： 10322199 DOI： 10.1016/S1369-5266(99)80022-3

Source DB: PubMed Journal: Curr Opin Plant Biol ISSN： 1369-5266 Impact factor: 7.834

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Cited

146 in total

1. Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants.

Authors: O Voinnet; Y M Pinto; D C Baulcombe
Journal: Proc Natl Acad Sci U S A Date: 1999-11-23 Impact factor: 11.205

Review 2. Molecular biology of weed control.

Authors: J Gressel
Journal: Transgenic Res Date: 2000 Impact factor: 2.788

10. Candidate gene polymorphisms associated with salt tolerance in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species.

Authors: Christian Lexer; Zhao Lai; Loren H Rieseberg
Journal: New Phytol Date: 2004-01 Impact factor: 10.151

Fast forward genetics based on virus-induced gene silencing.

1. Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants.

Review 2. Molecular biology of weed control.

3. Agricultural microbes genome 2: first glimpses into the genomes of plant-associated microbes.

4. Suppression of post-transcriptional gene silencing by a plant viral protein localized in the nucleus.

5. Virus-induced silencing of a plant cellulose synthase gene.

6. Targeted mRNA degradation by double-stranded RNA in vitro.

7. Detailed characterization of the posttranscriptional gene-silencing-related small RNA in a GUS gene-silenced tobacco.

Review 8. Chromosome regions and stress-related sequences involved in resistance to abiotic stress in Triticeae.

Review 9. RNA viruses as inducers, suppressors and targets of post-transcriptional gene silencing.

10. Candidate gene polymorphisms associated with salt tolerance in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species.