Literature DB >> 10322127

The PIK-related kinases intercept conventional signaling pathways.

F G Kuruvilla1, S L Schreiber.   

Abstract

Early efforts to place the first cloned mammalian PIK-related kinase, FRAP, into a conventional membrane to nuclear pathway met with little success. More recent data suggest that members of the family of PIK-related kinases act as intracellular sensors that govern radial and horizontal pathways. These pathways can impinge upon classical membrane to nuclear pathways, as well as components of the cell-cycle machinery.

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Year:  1999        PMID: 10322127     DOI: 10.1016/S1074-5521(99)80070-2

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  17 in total

1.  Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins.

Authors:  J S Hardwick; F G Kuruvilla; J K Tong; A F Shamji; S L Schreiber
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

2.  ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation.

Authors:  P Nghiem; P K Park; Y Kim ; C Vaziri; S L Schreiber
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

3.  Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR.

Authors:  Chi Kwan Tsang; Paula G Bertram; Wandong Ai; Ryan Drenan; X F Steven Zheng
Journal:  EMBO J       Date:  2003-11-17       Impact factor: 11.598

4.  Convergence of TOR-nitrogen and Snf1-glucose signaling pathways onto Gln3.

Authors:  Paula G Bertram; Jae H Choi; John Carvalho; Ting-Fung Chan; Wandong Ai; X F Steven Zheng
Journal:  Mol Cell Biol       Date:  2002-02       Impact factor: 4.272

5.  Endoplasmic reticulum and Golgi localization sequences for mammalian target of rapamycin.

Authors:  Xiangyu Liu; X F Steven Zheng
Journal:  Mol Biol Cell       Date:  2007-01-10       Impact factor: 4.138

6.  Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors.

Authors:  F G Kuruvilla; A F Shamji; S L Schreiber
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-19       Impact factor: 11.205

7.  The target of rapamycin signaling pathway regulates mRNA turnover in the yeast Saccharomyces cerevisiae.

Authors:  A R Albig; C J Decker
Journal:  Mol Biol Cell       Date:  2001-11       Impact factor: 4.138

8.  The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase.

Authors:  Jae H Choi; Paula G Bertram; Ryan Drenan; John Carvalho; Heather H Zhou; X F Steven Zheng
Journal:  EMBO Rep       Date:  2002-09-13       Impact factor: 8.807

Review 9.  Triterpenes in cancer: significance and their influence.

Authors:  Balraj Singh Gill; Sanjeev Kumar
Journal:  Mol Biol Rep       Date:  2016-06-25       Impact factor: 2.316

Review 10.  Phosphoinositide 3-kinase signaling in the vertebrate retina.

Authors:  Raju V S Rajala
Journal:  J Lipid Res       Date:  2010-01       Impact factor: 5.922

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