| Literature DB >> 10321037 |
N Gökhan1, H Erdoĝan, N T Durlu, R Demirdamar.
Abstract
Ten new benzoxazolinone derivatives having a disubstituted benzoyl group at the six position of the ring were synthesized by reacting 2-benzoxazolinone with aromatic carboxylic acids in the presence of polyphosphoric acid. The structure of the compounds were elucidated by IR, 1H NMR, MS and elemental analysis. Analgesic activity was evaluated by a modified Koster test. Seven compounds showed analgesic activities higher than that of acetylsalicylic acid.Entities:
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Year: 1999 PMID： 10321037 DOI： 10.1016/s0014-827x(98)00111-6
Source DB: PubMed Journal: Farmaco ISSN： 0014-827X