BACKGROUND AND PURPOSE: T1-weighted MR images show high signal intensity in the pallidum of many patients with liver cirrhosis. The purpose of this study was to evaluate quantitative changes in MR signals in patients with liver cirrhosis by using the magnetization transfer technique. METHODS: Magnetization transfer ratios were measured in seven different regions of the brain in 37 patients with liver cirrhosis and in 37 healthy volunteers. RESULTS: The magnetization transfer ratios in patients with liver cirrhosis were significantly lower than those in control subjects in the globus pallidus, putamen, thalamus, corona radiata, and subcortical white matter. CONCLUSION: Abnormal magnetization transfer ratios may be found in otherwise normal-appearing cerebral regions.
BACKGROUND AND PURPOSE: T1-weighted MR images show high signal intensity in the pallidum of many patients with liver cirrhosis. The purpose of this study was to evaluate quantitative changes in MR signals in patients with liver cirrhosis by using the magnetization transfer technique. METHODS: Magnetization transfer ratios were measured in seven different regions of the brain in 37 patients with liver cirrhosis and in 37 healthy volunteers. RESULTS: The magnetization transfer ratios in patients with liver cirrhosis were significantly lower than those in control subjects in the globus pallidus, putamen, thalamus, corona radiata, and subcortical white matter. CONCLUSION: Abnormal magnetization transfer ratios may be found in otherwise normal-appearing cerebral regions.
Authors: Vijay P B Grover; Mary M E Crossey; Julie A Fitzpatrick; Brian K Saxby; Roberta Shaw; Adam D Waldman; Marsha Y Morgan; Simon D Taylor-Robinson Journal: Metab Brain Dis Date: 2015-08-08 Impact factor: 3.584
Authors: F Miese; G Kircheis; H J Wittsack; F Wenserski; J Hemker; U Mödder; D Häussinger; M Cohnen Journal: AJNR Am J Neuroradiol Date: 2006-05 Impact factor: 3.825
Authors: D M Forton; N Patel; M Prince; A Oatridge; G Hamilton; J Goldblatt; J M Allsop; J V Hajnal; H C Thomas; M Bassendine; D E J Jones; S D Taylor-Robinson Journal: Gut Date: 2004-04 Impact factor: 23.059