Literature DB >> 10319890

Epstein-Barr virus meningoencephalitis with a lymphoma-like response in an immunocompetent host.

P D Schellinger1, C Sommer, F Leithäuser, S Schwab, B Storch-Hagenlocher, W Hacke, M Kiessling.   

Abstract

We report the clinical and neuropathological findings in an immunocompetent 19-year-old patient with a fatal acute Epstein-Barr virus (EBV) meningoencephalitis and a lymphoma-like B-lymphocyte response. Our results suggest that an immunotoxic rather than direct viral neuronal invasion mediates brain damage in EBV encephalitis and rule out primary central nervous system lymphoma (PCNSL) in our patient. We discuss immunosuppression as a therapeutic option, because present strategies mainly consist of symptomatic therapy due to unclear pathogenesis and nonavailability of effective antiviral agents.

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Year:  1999        PMID： 10319890     DOI： 10.1002/1531-8249(199905)45:5<659::aid-ana16>3.0.co;2-9

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  10 in total

1.  [Fulminant EBV meningoencephalitis : Good clinical outcome in a young, immunocompetent female].

Authors:  F Derler; S Seidel; D Bengel
Journal:  Nervenarzt       Date:  2017-10       Impact factor: 1.214

2.  A case of fulminant Epstein-Barr virus encephalitis in an immune-competent adult.

Authors:  Marvyn T Koning; Tessa Brik; Rogier Hagenbeek; Ido van den Wijngaard
Journal:  J Neurovirol       Date:  2019-01-22       Impact factor: 2.643

3.  Expanding the spectrum of neurological disease associated with Epstein-Barr virus activity.

Authors:  M Kleines; J Schiefer; A Stienen; M Blaum; K Ritter; M Häusler
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-05-15       Impact factor: 3.267

4.  Positive reaction for cysticercosis and multicentric anaplastic oligoastrocytoma.

Authors:  J Francisco Salomão; Marcos V Pone; André R A da Silva; René D Leibinger; Antonio R Bellas; João Maurício S Campos; José Roberto P Garrido; Elide Vanazzi; Ana C M W de Barros; Sheila M Pone; Márcia B Boechat
Journal:  Childs Nerv Syst       Date:  2005-03-19       Impact factor: 1.475

5.  Virological and immunological characteristics of fatal Epstein-Barr virus mononucleosis in a 17-year-old Caucasian male presenting with meningoencephalitis and hemophagocytic syndrome.

Authors:  Adriana Vince; Snjezana Zidovec Lepej; Ivan Kurelac; Bruno Barsic; Sanja Kozic; Igor Klinar; Kamelia Zarkovic
Journal:  J Neurovirol       Date:  2007-08       Impact factor: 2.643

6.  Case Report: Epstein-Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult.

Authors:  Lingtong Huang; Xuan Zhang; Xueling Fang
Journal:  Front Immunol       Date:  2021-02-25       Impact factor: 7.561

7.  Oculomotor Nerve Palsy as a Presenting Symptom of Epstein-Barr Virus-Associated Infectious Mononucleosis: Case Report and Review of the Literature.

Authors:  Leon Amadeus Steiner; Aslihan Erbay; Florence Pache; Moritz Niederschweiberer; Eberhard Siebert; Karen Gertz; Klemens Ruprecht
Journal:  Case Rep Neurol       Date:  2021-11-29

8.  A Rare Case of Epstein-Barr Virus: Infectious Mononucleosis Complicated by Guillain-Barré Syndrome.

Authors:  Oluseyi Abidoye; Erine Raybon-Rojas; Henry Ogbuagu
Journal:  Cureus       Date:  2022-01-10

9.  Epstein-Barr virus-associated infectious mononucleosis with acute epididymitis: a case report.

Authors:  Kentaro Sako; Tsuneaki Kenzaka; Ayako Kumabe
Journal:  BMC Infect Dis       Date:  2022-02-10       Impact factor: 3.090

Review 10.  The spectrum of Epstein-Barr virus infections of the central nervous system after organ transplantation.

Authors:  Mohamed Ridha; Dylan G Jones; David P Lerner; Michal Vytopil; Barbara Voetsch; Joseph D Burns; Anil Ramineni; Pooja Raibagkar
Journal:  Virol J       Date:  2021-08-06       Impact factor: 4.099
  10 in total

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