Literature DB >> 10319160

Synthesis of Mannich bases of antineoplaston A10 and their antitumor activity.

B G Choi1, H K Seo, B H Chung, S U Choi, C O Lee.   

Abstract

Some Mannich bases of Antineoplaston A10 which is antitumor agent under clinical investigation were synthesized and tested for cytotoxicity. The tested compounds (2a, 2b, 2d) showed good activity comparable to that of carboplatin.

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Year:  1994        PMID： 10319160     DOI： 10.1007/bf02979127

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  4 in total

1.  Antineoplastons: biochemical defense against cancer.

Authors:  S R Burzynski
Journal:  Physiol Chem Phys       Date:  1976

2.  Biologically active peptides in human urine. I. Isolation of a group of medium-sized peptides.

Authors:  S R Burzynski
Journal:  Physiol Chem Phys       Date:  1973

3.  [Potential cytostatics from aminomethylation of NH-acid hypnotica].

Authors:  W Werner; H Fritzsche
Journal:  Arch Pharm Ber Dtsch Pharm Ges       Date:  1969-03

4.  Synthesis and antitumor properties of N1-acyloxymethyl derivatives of bis(2,6-dioxopiperazines).

Authors:  J C Cai; H L Shu; C F Tang; T Komatsu; T Matsuno; T Narita; S Yaguchi; Y Koide; M Takase
Journal:  Chem Pharm Bull (Tokyo)       Date:  1989-11       Impact factor: 1.645
  4 in total
  1 in total

1.  Synthesis of (-)-julocrotine and a diversity oriented Ugi-approach to analogues and probes.

Authors:  Ricardo A W Neves Filho; Bernhard Westermann; Ludger A Wessjohann
Journal:  Beilstein J Org Chem       Date:  2011-11-07       Impact factor: 2.883
  1 in total

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