Literature DB >> 10319130

Hepatoprotective effect of Vitex negundo against carbon tetrachloride-induced liver damage.

Y Avadhoot1, A C Rana.   

Abstract

Alcoholic extract of the seeds of Vitex negundo Linn. was obtained by cold maceration. A dose of 250 mg/kg (1/6 of LD50) of the extract was selected to study the hepatoprotective action against carbon tetrachloride-induced liver damage. The extract was found to be effective in preventing liver damage which was evident by morphological, biochemical and functional parameters.

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Year:  1991        PMID： 10319130     DOI： 10.1007/bf02857823

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  3 in total

1.  Studies on Acorus calamus (III); some pharmacological actions of the volatile oil.

Authors:  P C DANDIYA; H CULLUMBINE
Journal:  J Pharmacol Exp Ther       Date:  1959-04       Impact factor: 4.030

2.  Pharmacological study and fractionation of Paspalum scrobiculatum extract.

Authors:  N K BHIDE
Journal:  Br J Pharmacol Chemother       Date:  1962-02

3.  Effect of Mn++ on blood sugar level in rats.

Authors:  K Mogre; S J Kashalikar; S M Kendurkar
Journal:  Indian J Physiol Pharmacol       Date:  1982 Jul-Sep
  3 in total
  7 in total

1.  Negundoside, an irridiod glycoside from leaves of Vitex negundo, protects human liver cells against calcium-mediated toxicity induced by carbon tetrachloride.

Authors:  Sheikh A Tasduq; Peerzada J Kaiser; Bishan D Gupta; Vijay K Gupta; Rakesh K Johri
Journal:  World J Gastroenterol       Date:  2008-06-21       Impact factor: 5.742

2.  The efficient biogeneration of Ag and NiO nanoparticles from VPLE and a study of the anti-diabetic properties of the extract.

Authors:  Hongying Gao; Reza Tayebee; Mojtaba Fattahi Abdizadeh; Esrafil Mansouri; Maryam Latifnia; Zahra Pourmojahed
Journal:  RSC Adv       Date:  2020-01-16       Impact factor: 4.036

3.  Effect of oral administration of ethanolic extract of Vitex negundo on thioacetamide-induced nephrotoxicity in rats.

Authors:  Farkaad A Kadir; Normadiah M Kassim; Mahmood A Abdulla; Wageeh A Yehye
Journal:  BMC Complement Altern Med       Date:  2013-10-30       Impact factor: 3.659

4.  Active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking.

Authors:  Thangaraj Vinuchakkaravarthy; Kaliya Perumal Kumaravel; Samuthirapandian Ravichandran; Devadasan Velmurugan
Journal:  Bioinformation       Date:  2011-10-14

Review 5.  Traditional Medicinal Uses, Phytochemistry, Biological Properties, and Health Applications of Vitex sp.

Authors:  Nurkhalida Kamal; Nurul Syahidah Mio Asni; Ivana Nur Allisya Rozlan; Muhammad Aniq Hamzah Mohd Azmi; Noor Wini Mazlan; Ahmed Mediani; Syarul Nataqain Baharum; Jalifah Latip; Suvik Assaw; Ru Angelie Edrada-Ebel
Journal:  Plants (Basel)       Date:  2022-07-26

6.  Hepatoprotective Role of Ethanolic Extract of Vitex negundo in Thioacetamide-Induced Liver Fibrosis in Male Rats.

Authors:  Farkaad A Kadir; Normadiah M Kassim; Mahmood A Abdulla; Wageeh A Yehye
Journal:  Evid Based Complement Alternat Med       Date:  2013-05-19       Impact factor: 2.629

7.  PASS-predicted Vitex negundo activity: antioxidant and antiproliferative properties on human hepatoma cells--an in vitro study.

Authors:  Farkaad A Kadir; Normadiah M Kassim; Mahmood A Abdulla; Wageeh A Yehye
Journal:  BMC Complement Altern Med       Date:  2013-12-04       Impact factor: 3.659
  7 in total

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