Literature DB >> 10319129

Hepatoprotective effects of Andrographis paniculata against carbon tetrachloride-induced liver damage.

A C Rana1, Y Avadhoot.   

Abstract

Alcoholic extract of the leaves of Andrographis paniculata Ness (= AAP) was obtained by cold maceration. A dose of 300 mg/kg (1/6 of LD50) of the extract was selected to study hepatoprotective action against carbon tetrachloride-induced liver damage. The extract was found to be effective in preventing liver damage which was evident by morphological, biochemical and functional parameters.

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Year:  1991        PMID： 10319129     DOI： 10.1007/bf02857822

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  3 in total

1.  In vivo and in vitro effects of kalmegh (Andrographis paniculata) extract and andrographolide on hepatic microsomal drug metabolizing enzymes.

Authors:  B R Choudhury; S J Haque; M K Poddar
Journal:  Planta Med       Date:  1987-04       Impact factor: 3.352

2.  Pharmacological study and fractionation of Paspalum scrobiculatum extract.

Authors:  N K BHIDE
Journal:  Br J Pharmacol Chemother       Date:  1962-02

3.  Andrographolide and kalmegh (Andrographis paniculata) extract: effect on intestinal brush-border membrane-bound hydrolases.

Authors:  B R Choudhury; M K Poddar
Journal:  Methods Find Exp Clin Pharmacol       Date:  1985-12
  3 in total
  11 in total

1.  Survey and scientific evaluation of medicinal plants used by the Pahan and Teli tribal communities of Natore district, Bangladesh.

Authors:  Mohammed Rahmatullah; Zubaida Khatun; Abid Hasan; Waheda Parvin; Md Moniruzzaman; Asha Khatun; Mostafi Jumrut Mahal; Md Shaiful Alam Bhuiyan; Sadia Moin Mou; Rownak Jahan
Journal:  Afr J Tradit Complement Altern Med       Date:  2012-04-02

2.  Open label clinical trial to study adverse effects and tolerance to dry powder of the aerial part of andrographis paniculata in patients type 2 with diabetes mellitus.

Authors:  Renu Agarwal; Siti Amrah Sulaiman; Mafauzy Mohamed
Journal:  Malays J Med Sci       Date:  2005-01

3.  Andrographolide suppresses epithelial mesenchymal transition by inhibition of MAPK signalling pathway in lens epithelial cells.

Authors:  Forum Kayastha; Kaid Johar; Devarshi Gajjar; Anshul Arora; Hardik Madhu; Darshini Ganatra; Abhay Vasavada
Journal:  J Biosci       Date:  2015-06       Impact factor: 1.826

4.  Anti-cancer activity of heteroaromatic acetals of andrographolide and its isomers.

Authors:  Nitesh Tamang; Christopher Andrews; Sai Kiran Mavileti; Srinivas Nanduri; Nageswara Rao Golakoti; Balasubramanyam Karanam
Journal:  New J Chem       Date:  2022-04-22       Impact factor: 3.925

5.  Simultaneous estimation of andrographolide and wedelolactone in herbal formulations.

Authors:  M B Patel; V M Kadakia; S H Mishra
Journal:  Indian J Pharm Sci       Date:  2008-09       Impact factor: 0.975

6.  Traditional herbal medicine in far-west Nepal: a pharmacological appraisal.

Authors:  Ripu M Kunwar; Keshab P Shrestha; Rainer W Bussmann
Journal:  J Ethnobiol Ethnomed       Date:  2010-12-13       Impact factor: 2.733

7.  Hepatoprotective effect of poly herbal formulation against various hepatotoxic agents in rats.

Authors:  Anil U Tatiya; Sanjay J Surana; Manisha P Sutar; Nehal H Gamit
Journal:  Pharmacognosy Res       Date:  2012-01

8.  The anti-inflammatory effect of Andrographis paniculata (Burm. f.) Nees on pelvic inflammatory disease in rats through down-regulation of the NF-κB pathway.

Authors:  Wei Zou; Zuoqi Xiao; Xiaoke Wen; Jieying Luo; Shuqiong Chen; Zeneng Cheng; Daxiong Xiang; Jian Hu; Jingyu He
Journal:  BMC Complement Altern Med       Date:  2016-11-25       Impact factor: 3.659

9.  Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide.

Authors:  Thanasekaran Jayakumar; Cheng-Ying Hsieh; Jie-Jen Lee; Joen-Rong Sheu
Journal:  Evid Based Complement Alternat Med       Date:  2013-03-24       Impact factor: 2.629

Review 10.  Andrographis paniculata (Burm. f.) Wall. ex Nees: a review of ethnobotany, phytochemistry, and pharmacology.

Authors:  Md Sanower Hossain; Zannat Urbi; Abubakar Sule; K M Hafizur Rahman
Journal:  ScientificWorldJournal       Date:  2014-12-24
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