Literature DB >> 10319017

Therapeutic potential of the anti-angiogenesis drug TNP-470.

P Gervaz1, C Fontolliet.   

Abstract

Neovessel formation is a pre-requisite for tumour growth and dissemination. Inhibition of angiogenesis is a promising approach for the treatment of neoplasms. In recent years, antiangiogenic drugs, such as TNP-470, have entered clinical trials. In this paper, we review the key experimental and clinical data on the role of TNP-470 in anti-tumour treatment.

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Year:  1998        PMID： 10319017      PMCID： PMC3220376          DOI： 10.1046/j.1365-2613.1998.00087.x

Source DB:  PubMed          Journal:  Int J Exp Pathol        ISSN： 0959-9673            Impact factor:   1.925


  6 in total

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Journal:  Chem Biol       Date:  2006-09

2.  Antiangiogenic therapy for human pancreatic carcinoma xenografts in nude mice.

Authors:  Lin Jia; Mei-Hua Zhang; Shi-Zhen Yuan; Wen-Ge Huang
Journal:  World J Gastroenterol       Date:  2005-01-21       Impact factor: 5.742

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5.  Angiogenesis is an independent prognostic factor in malignant mesothelioma.

Authors:  J G Edwards; G Cox; A Andi; J L Jones; R A Walker; D A Waller; K J O'Byrne
Journal:  Br J Cancer       Date:  2001-09-14       Impact factor: 7.640

6.  Maternal administration of anti-angiogenic agents, TNP-470 and Angiostatin4.5, induces fetal microphthalmia.

Authors:  Catrin S Rutland; Keyi Jiang; Gerald A Soff; Christopher A Mitchell
Journal:  Mol Vis       Date:  2009-06-26       Impact factor: 2.367
  6 in total

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