Literature DB >> 103121

Effects of benzazepine (Sch-12679) on shock-induced fighting and locomotor behavior in rats.

N J Bean, K Loman, R Conner.   

Abstract

Benzazepine (Sch-12679) reduced the shock-induced fighting behavior of rats in a dose-dependent fashion. However, the drug also impaired both locomotor behavior and rotorod performance. These results suggest that the aggression suppressive effects of Sch-12679 may be mediated by drug-induced sedation.

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Year:  1978        PMID: 103121     DOI: 10.1007/bf00427756

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  6 in total

1.  Effects of a novel anti-aggressive agent upon two types of brain stimulated emotional behavior.

Authors:  R J Katz; E Thomas
Journal:  Psychopharmacology (Berl)       Date:  1976-07-09       Impact factor: 4.530

Review 2.  The neuropharmacology of aggression: a critical review.

Authors:  H H Avis
Journal:  Psychol Bull       Date:  1974-01       Impact factor: 17.737

3.  The behavioral pharmacology of Sch 12679. A new psychoactive agent.

Authors:  A Barnett; R I Taber; S S Steiner
Journal:  Psychopharmacologia       Date:  1974-05-15

4.  Therapeutic trials and EEG investigations with SCH-12,679 in behaviorally disturbed adolescents.

Authors:  T M Itil; M J Stock; A D Duffy; A Esquenazi; B Saleuty; T H Han
Journal:  Curr Ther Res Clin Exp       Date:  1972-03

5.  A clinical trial of a benzazepine (SCH 12679) in acute schizophrenic patients.

Authors:  S Park; S Gershon; A Floyd
Journal:  Curr Ther Res Clin Exp       Date:  1972-06

6.  Clinical, toxicological and electroencephalographic study with SCH-12,679 in chronic schizophrenics.

Authors:  A Keskiner; T M Itil; T H Han; B Saletu; W Hsu
Journal:  Curr Ther Res Clin Exp       Date:  1971-11
  6 in total

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