Literature DB >> 1030402

Behavioral testing as a method for assessing risk.

R E Butcher.   

Abstract

Behavioral effects have been found to result from the prenatal administration of substances known to be teratogenic to the CNS. These effects occur at dose levels lower than those producing gross malformations and when the agent is administered at times other than that optimal for CNS relevant technique for detecting adverse consequences of prenatal exposure to drugs and chemicals. Behavioral testing, however, also appears to have attributes that dictate a thoughtful approach to its role as a method for assessing risk, and additional research is needed to obtain usable techniques. The need for such research is intensified by the present inability to identify potential behavioral teratogens by means other than laboratory investigation.

Entities:  

Mesh:

Substances:

Year:  1976        PMID: 1030402      PMCID: PMC1475305          DOI: 10.1289/ehp.761875

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  4 in total

1.  Some behavioral effects of maternal hypervitaminosis A in rats.

Authors:  C V Vorhees
Journal:  Teratology       Date:  1974-12

2.  The effects of vitamin A excess administered during the mid-fetal period on learning and development in rat offspring.

Authors:  D E Hutchings; J Gaston
Journal:  Dev Psychobiol       Date:  1974-05       Impact factor: 3.038

3.  Maternal vitamin A excess during the early fetal period: effects on learning and development in the offspring.

Authors:  D E Hutchings; J Gibbon; M A Kaufman
Journal:  Dev Psychobiol       Date:  1973-09       Impact factor: 3.038

4.  A learning impairment associated with maternal hypervitaminosis-A in rats.

Authors:  R E Butcher; R L Brunner; T Roth; C A Kimmel
Journal:  Life Sci I       Date:  1972-02-01
  4 in total
  3 in total

1.  A developmental toxicity and psychotoxicity evaluation of FD and C red dye #3 (erythrosine) in rats.

Authors:  C V Vorhees; R E Butcher; R L Brunner; V Wootten; T J Sobotka
Journal:  Arch Toxicol       Date:  1983-08       Impact factor: 5.153

Review 2.  Prospective, longitudinal assessment of developmental neurotoxicity.

Authors:  J L Jacobson; S W Jacobson
Journal:  Environ Health Perspect       Date:  1996-04       Impact factor: 9.031

3.  Research strategies for behavioral teratology studies.

Authors:  L D Grant
Journal:  Environ Health Perspect       Date:  1976-12       Impact factor: 9.031

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.