Literature DB >> 103004

The arrangement and rearrangement of antibody genes.

J G Seidman, P Leder.   

Abstract

Cloned segments of mouse chromosomal DNA provide direct evidence for the somatic rearrangement of kappa variable and constant region genes in antibody producing cells. This rearrangement apparently affects only one member of an allelic pair of light chain genes.

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Year:  1978        PMID: 103004     DOI: 10.1038/276790a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  74 in total

Review 1.  Receptor selection in B and T lymphocytes.

Authors:  D Nemazee
Journal:  Annu Rev Immunol       Date:  2000       Impact factor: 28.527

2.  Comparison of mRNA precursors in plasmacytomas producing closely related kappa chains.

Authors:  R P Perry; D E Kelley; U Schibler
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

3.  Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

Authors:  E E Max; J G Seidman; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1979-07       Impact factor: 11.205

4.  Cloning of immunoglobulin kappa light chain genes from mouse liver and myeloma MOPC 173.

Authors:  M Steinmetz; H G Zachau; B Mach
Journal:  Nucleic Acids Res       Date:  1979-07-25       Impact factor: 16.971

5.  Regulation of kappa immunoglobulin gene transcription in vitro.

Authors:  R A Currie
Journal:  Nucleic Acids Res       Date:  1990-05-25       Impact factor: 16.971

6.  Functional modularity in the SP6 kappa promoter.

Authors:  E Högbom; A C Magnusson; T Leanderson
Journal:  Nucleic Acids Res       Date:  1991-08-25       Impact factor: 16.971

7.  Alternative splicing patterns in an aberrantly rearranged immunoglobulin kappa-light-chain gene.

Authors:  S K Sikder; E A Kabat; S L Morrison
Journal:  Proc Natl Acad Sci U S A       Date:  1985-06       Impact factor: 11.205

8.  Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures.

Authors:  J C Young; O N Witte
Journal:  Mol Cell Biol       Date:  1988-10       Impact factor: 4.272

9.  Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

Authors:  H Potter; L Weir; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

10.  The gamma 1 heavy-chain disease FOR protein is present in two molecular forms.

Authors:  J Zikán; L Rozprimová; J Novotný
Journal:  Folia Microbiol (Praha)       Date:  1984       Impact factor: 2.099

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