Literature DB >> 1028160

Cytogenetically marked clones in human fibroblasts cultured from normal subjects.

D G Harnden, P A Benn, J M Oxford, A M Taylor, T P Webb.   

Abstract

Clones of cytogenetically abnormal cells have been recognized in fibroblasts cultured from normal human adult skin. No such clones have been observed in human embryo skin fibroblasts cultured in the same way. Although the culture conditions may have played some part in the emergence of these clones, it is possible that the abnormal cells from which the clones were derived were present in vivo.

Entities:  

Mesh：

Year:  1976        PMID： 1028160     DOI： 10.1007/BF01539242

Source DB:  PubMed          Journal:  Somatic Cell Genet        ISSN： 0098-0366


  15 in total

1.  Origin of multidrug resistance in cells with and without multidrug resistance genes: chromosome reassortments catalyzed by aneuploidy.

Authors:  P Duesberg; R Stindl; R Hehlmann
Journal:  Proc Natl Acad Sci U S A       Date:  2001-09-11       Impact factor: 11.205

2.  Abnormal skin fibroblast cytogenetics in four dysmorphic patients with normal lymphocyte chromosomes.

Authors:  R A Pagon; J G Hall; S L Davenport; J Aase; T H Norwood; H W Hoehn
Journal:  Am J Hum Genet       Date:  1979-01       Impact factor: 11.025

3.  Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos.

Authors:  P A Benn
Journal:  Am J Hum Genet       Date:  1976-09       Impact factor: 11.025

4.  Overreplication and recombination of DNA in higher eukaryotes: potential consequences and biological implications.

Authors:  R T Schimke; S W Sherwood; A B Hill; R N Johnston
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

5.  Chromosome translocations in fibroblast cultures derived from patients with Werner's syndrome.

Authors:  P A Benn
Journal:  Am J Hum Genet       Date:  1985-01       Impact factor: 11.025

6.  Ring 11 chromosome (46,xx,r11(p15q25)).

Authors:  M Valente; H Muller; R S Sparkes
Journal:  Hum Genet       Date:  1977-05-10       Impact factor: 4.132

Review 7.  Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations.

Authors:  D Salk
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

8.  Successive spontaneous abortions including one with whole-arm translocation between chromosomes 2.

Authors:  K Ohama; I Kusumi; H Takahara; T Kajii
Journal:  Hum Genet       Date:  1978-01-19       Impact factor: 4.132

Review 9.  Cancer genes generated by rare chromosomal rearrangements rather than activation of oncogenes.

Authors:  P H Duesberg
Journal:  Med Oncol Tumor Pharmacother       Date:  1987

Review 10.  Cancer genes: rare recombinants instead of activated oncogenes (a review).

Authors:  P H Duesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205
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