Literature DB >> 102747

The pathology of experimental Ebola virus infection in monkeys.

A Baskerville, E T Bowen, G S Platt, L B McArdell, D I Simpson.   

Abstract

Six rhesus and two vervet monkeys were infected intraperitoneally with Ebola virus. They developed an acute haemorrhagic fever with skin rash 4 days later and died 6--12 days after infection. Histopathological lesions of acute necrosis were present in the liver, spleen, lymph nodes, lungs and testes. The presence of fibrin thrombi in several organs was suggestive of the occurrence of disseminated intravascular coagulation during the infection.

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Year:  1978        PMID: 102747     DOI: 10.1002/path.1711250303

Source DB:  PubMed          Journal:  J Pathol        ISSN: 0022-3417            Impact factor:   7.996


  34 in total

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5.  Particle-to-PFU ratio of Ebola virus influences disease course and survival in cynomolgus macaques.

Authors:  Kendra J Alfson; Laura E Avena; Michael W Beadles; Hilary Staples; Jerritt W Nunneley; Anysha Ticer; Edward J Dick; Michael A Owston; Christopher Reed; Jean L Patterson; Ricardo Carrion; Anthony Griffiths
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7.  Ebola: history, treatment, and lessons from a new emerging pathogen.

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8.  Peripheral Neuronopathy Associated With Ebola Virus Infection in Rhesus Macaques: A Possible Cause of Neurological Signs and Symptoms in Human Ebola Patients.

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9.  Experimental respiratory Marburg virus haemorrhagic fever infection in the common marmoset (Callithrix jacchus).

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Review 10.  Post-exposure treatments for Ebola and Marburg virus infections.

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