Literature DB >> 102630

Clavulanic acid inhibition of beta-lactamase I from Bacillus cereus 569/H.

J P Durkin, T Viswanatha.   

Abstract

Inactivation of beta-lactamase I by clavulanic acid was investigated. Clavulanic acid induced inhibition of the enzyme was found to be progressive with time. Benzylpenicillin provided protection against the adverse effects of the inhibitor initially, however, the enzyme was irreversibly inhibited in a progressive manner even in the presence of substrate. Reaction of beta-lactamase I with clavulanic acid, in the presence of ampicillin, led to a very rapid inactivation of the enzyme.

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Year:  1978        PMID： 102630     DOI： 10.7164/antibiotics.31.1162

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

Review 1.  Beta-lactamase inhibitors from laboratory to clinic.

Authors:  K Bush
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

Review 2.  Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition.

Authors:  Carine Bebrone; Patricia Lassaux; Lionel Vercheval; Jean-Sébastien Sohier; Adrien Jehaes; Eric Sauvage; Moreno Galleni
Journal:  Drugs       Date:  2010-04-16       Impact factor: 9.546

Review 3.  Antibiotic resistance in pathogenic and producing bacteria, with special reference to beta-lactam antibiotics.

Authors:  H Ogawara
Journal:  Microbiol Rev       Date:  1981-12

4.  In vitro activity of ceftazidime-avibactam combination in in vitro checkerboard assays.

Authors:  Johanna Berkhout; Maria J Melchers; Anita C van Mil; Wright W Nichols; Johan W Mouton
Journal:  Antimicrob Agents Chemother       Date:  2014-12-08       Impact factor: 5.191

5.  Supramolecular antibiotics: a strategy for conversion of broad-spectrum to narrow-spectrum antibiotics for Staphylococcus aureus.

Authors:  Thameez M Koyasseril-Yehiya; Alam García-Heredia; Francesca Anson; Poornima Rangadurai; M Sloan Siegrist; S Thayumanavan
Journal:  Nanoscale       Date:  2020-10-22       Impact factor: 7.790

Review 6.  Three decades of beta-lactamase inhibitors.

Authors:  Sarah M Drawz; Robert A Bonomo
Journal:  Clin Microbiol Rev       Date:  2010-01       Impact factor: 26.132

7.  Kinetics of inactivation of beta-lactamase I by 6 beta-bromopenicillanic acid.

Authors:  V Knott-Hunziker; B S Orlek; P G Sammes; S G Waley
Journal:  Biochem J       Date:  1980-06-01       Impact factor: 3.857

8.  Treatment of urinary tract infections with a combination of amoxicillin and clavulanic acid.

Authors:  A Iravani; G A Richard
Journal:  Antimicrob Agents Chemother       Date:  1982-10       Impact factor: 5.191

9.  Screening and characterization of microorganisms with glutaryl-7ADCA acylase activity.

Authors:  G Franzosi; E Battistel; I Gagliardi; W Van der Goes
Journal:  Appl Microbiol Biotechnol       Date:  1995-07       Impact factor: 4.813
  9 in total

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