[New growth of interneuronal connections in the neocortex of adult rats under conditions of secondary epileptogenesis].

The synaptic organization of the parietal cortex in the zone of a chronic mirror epileptic focus was studied in rats electron microscopically. The synaptoarchitectonics was found to change as compared with control material in the mirror focus. Part of synapses were reduced due to degeneration of interhemisphere fibres. The amount of fine preterminal axons and axo-axonal contacts increased, the organization of complex synaptic conjunction grew more complicated. These data suggest possible newformation of interneuronal connections under the influence of an intensive stream of impulses from the primary focus.