PURPOSE:Sevoflurane is a volatile anesthetic agent, which combines rapid, smooth inhalational induction of anesthesia with rapid recovery, making it particularly suitable for day case anesthesia. The laryngeal mask airway is often also used in ambulatory anesthesia, with intravenous propofol being the agent of choice for its insertion. Our objective was to compare the conditions for laryngeal mask airway (LMA) insertion obtained by modified vital capacity breath sevoflurane inhalational induction of anesthesia with propofol intravenous induction. METHODS:Eighty-eight patients, aged 18-65 yr, ASA I-II, undergoing general anesthesia for elective surgery were randomized into two groups in a prospective, single-blind study. Patients in Group P (n=44) received 2.5 mg x kg(-1) propofol i.v. and in Group S (n=44) received sevoflurane 8% in nitrous oxide 50% and oxygen. Ventilation was not assisted. Laryngeal mask airway insertion was attempted at one minute intervals from loss of both verbal response and eyelash reflex, by an anesthesiologist unaware of the induction technique. Complications, such as coughing and head movement, were also noted at each attempt. RESULTS:Mean time to successful LMA insertion was 1.3 (1-3) min in P and 2.2 (1-3) min in S, P < 0.05. Eleven patients in Group P, (25%) required additional propofol compared with four (9%) in S, P < 0.05. Incidence of complications was similar in both groups and by 3 min, LMA was successfully inserted in all patients. CONCLUSION: Modified vital capacity breath inhalational induction with sevoflurane 8% is efficient for LMA insertion in most cases, but takes slightly longer than propofol.
RCT Entities:
PURPOSE:Sevoflurane is a volatile anesthetic agent, which combines rapid, smooth inhalational induction of anesthesia with rapid recovery, making it particularly suitable for day case anesthesia. The laryngeal mask airway is often also used in ambulatory anesthesia, with intravenous propofol being the agent of choice for its insertion. Our objective was to compare the conditions for laryngeal mask airway (LMA) insertion obtained by modified vital capacity breath sevoflurane inhalational induction of anesthesia with propofol intravenous induction. METHODS: Eighty-eight patients, aged 18-65 yr, ASA I-II, undergoing general anesthesia for elective surgery were randomized into two groups in a prospective, single-blind study. Patients in Group P (n=44) received 2.5 mg x kg(-1) propofol i.v. and in Group S (n=44) received sevoflurane 8% in nitrous oxide 50% and oxygen. Ventilation was not assisted. Laryngeal mask airway insertion was attempted at one minute intervals from loss of both verbal response and eyelash reflex, by an anesthesiologist unaware of the induction technique. Complications, such as coughing and head movement, were also noted at each attempt. RESULTS: Mean time to successful LMA insertion was 1.3 (1-3) min in P and 2.2 (1-3) min in S, P < 0.05. Eleven patients in Group P, (25%) required additional propofol compared with four (9%) in S, P < 0.05. Incidence of complications was similar in both groups and by 3 min, LMA was successfully inserted in all patients. CONCLUSION: Modified vital capacity breath inhalational induction with sevoflurane 8% is efficient for LMA insertion in most cases, but takes slightly longer than propofol.