Literature DB >> 10231255

Randomised controlled trial of educational package on management of menorrhagia in primary care: the Anglia menorrhagia education study.

G R Fender1, A Prentice, T Gorst, R M Nixon, S W Duffy, N E Day, S K Smith.   

Abstract

OBJECTIVE: To determine whether an educational package could influence the management of menorrhagia, increase the appropriateness of choice of non-hormonal treatment, and reduce referral rates from primary to secondary care.
DESIGN: Randomised controlled trial.
SETTING: General practices in East Anglia.
SUBJECTS: 100 practices (348 doctors) in primary care were recruited and randomised to intervention (54) and control (46).
INTERVENTIONS: An educational package based on principles of "academic detailing" with independent academics was given in small practice based interactive groups with a visual presentation, a printed evidence based summary, a graphic management flow chart, and a follow up meeting at 6 months. OUTCOME MEASURES: All practices recorded consultation details, treatments offered, and outcomes for women with regular heavy menstrual loss (menorrhagia) over 1 year.
RESULTS: 1001 consultation data sheets for menorrhagia were returned. There were significantly fewer referrals (20% v 29%; odds ratio 0. 64; 95% confidence interval 0.41 to 0.99) and a significantly higher use of tranexamic acid (odds ratio 2.38; 1.61 to 3.49) in the intervention group but no overall difference in norethisterone treatment compared with controls. There were more referrals when tranexamic acid was given with norethisterone than when it was given alone. Those practices reporting fewer than 10 cases showed the highest increase in prescribing of tranexamic acid.
CONCLUSIONS: The educational package positively influenced referral for menorrhagia and treatment with appropriate non-hormonal drugs.

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Year:  1999        PMID: 10231255      PMCID: PMC27863          DOI: 10.1136/bmj.318.7193.1246

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  28 in total

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2.  Economic and policy analysis of university-based drug "detailing".

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3.  Predictors of physician prescribing change in an educational experiment to improve medication use.

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5.  The mortality risk associated with hysterectomy.

Authors:  P A Wingo; C M Huezo; G L Rubin; H W Ory; H B Peterson
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6.  Menstrual blood loss--a population study. Variation at different ages and attempts to define normality.

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7.  Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid.

Authors:  J Bonnar; B L Sheppard
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8.  The effects of mefenamic acid and norethisterone on measured menstrual blood loss.

Authors:  I T Cameron; R Haining; M A Lumsden; V R Thomas; S K Smith
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9.  The effects of danazol, mefenamic acid, norethisterone and a progesterone-impregnated coil on endometrial prostaglandin concentrations in women with menorrhagia.

Authors:  I T Cameron; R Leask; R W Kelly; D T Baird
Journal:  Prostaglandins       Date:  1987-07

Review 10.  Dysfunctional uterine bleeding.

Authors:  I T Cameron
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  20 in total

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5.  Management of menorrhagia: an audit of practices in the Anglia menorrhagia education study.

Authors:  G R Fender; A Prentice; R M Nixon; T Gorst; S W Duffy; N E Day; S K Smith
Journal:  BMJ       Date:  2001-03-03

6.  An integrated care pathway for menorrhagia across the primary-secondary interface: patients' experience, clinical outcomes, and service utilisation.

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Review 9.  Educational outreach visits: effects on professional practice and health care outcomes.

Authors:  M A O'Brien; S Rogers; G Jamtvedt; A D Oxman; J Odgaard-Jensen; D T Kristoffersen; L Forsetlund; D Bainbridge; N Freemantle; D A Davis; R B Haynes; E L Harvey
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Review 10.  Benefits and risks of pharmacological agents used for the treatment of menorrhagia.

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