| Literature DB >> 10230637 |
R Iori1, R Bernardi, D Gueyrard, P Rollin, S Palmieri.
Abstract
A new semi-synthetic way to produce glucoraphanin (2), the bio-precursor of the potential anticarcinogen sulforaphane (3), has been developed. Starting from glucoerucin (1), isolated from ripe seeds of Eruca sativa, glucoraphanin was obtained through chemoselective oxidation. Controlled myrosinase-catalysed hydrolysis of this precursor quantitatively afforded sulforaphane.Entities:
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Year: 1999 PMID： 10230637 DOI： 10.1016/s0960-894x(99)00136-5
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823