Literature DB >> 10228366

[The behavior of Trypanosoma cruzi parasitemia in chronic chagasics over 13 years].

C Castro1, V Macêdo, A Prata.   

Abstract

The parasitemia of 202 chronic chagasics was studied for approximately 13 years by repeated conventional xenodiagnoses. Mean patient age was 41.1 years. They lived in an endemic area; 124 were females and 78 were males. It was seen that the level of parasitemia oscillated. It went up in 14 individuals, went down in 42 and stayed at the same level in 146. In general the parasitemia was reduced. The percentage of xenopositive chagasics, which was 37.6%, 48.5%, and 51% in the first, second and third xenodiagnosis, respectively, in 1976/78, changed to 30.2% in 1988/91 (p = 0.00003). The percentage of positive pools, which was 15.2%, 20.9%, 20.8% in the first, second and third xenodiagnosis, respectively, in 1976/78, changed to 10.4% in 1988/91, (p = 0.00000001). There were 62 patients whose xenodiagnoses were all negative and 23 whose exams were all positive. The percentage of chagasics with high, medium and low parasitemia, which in 1976/78 was 9.4%, 20.8% and 69.8%, respectively, changed to 4.4%, 12.9% and 82.7%, respectively, in 1988/91.

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Year:  1999        PMID: 10228366     DOI: 10.1590/s0037-86821999000200007

Source DB:  PubMed          Journal:  Rev Soc Bras Med Trop        ISSN: 0037-8682            Impact factor:   1.581


  7 in total

1.  Detection of parasitemia profiles by blood culture after treatment of human chronic Trypanosoma cruzi infection.

Authors:  Ana Maria de Castro; Alejandro Ostermayer Luquetti; Anis Rassi; Egler Chiari; Lúcia Maria da Cunha Galvão
Journal:  Parasitol Res       Date:  2006-03-29       Impact factor: 2.289

2.  Influence of pregnancy on Trypanosoma cruzi parasitemia in chronically infected women in a rural Bolivian community.

Authors:  Laurent Brutus; Jean-Christophe Ernould; Jorge Postigo; Mario Romero; Dominique Schneider; José-Antonio Santalla
Journal:  Am J Trop Med Hyg       Date:  2011-05       Impact factor: 2.345

3.  Risk progression to chronic Chagas cardiomyopathy: influence of male sex and of parasitaemia detected by polymerase chain reaction.

Authors:  A L Basquiera; A Sembaj; A M Aguerri; M Omelianiuk; S Guzmán; J Moreno Barral; T F Caeiro; R J Madoery; O A Salomone
Journal:  Heart       Date:  2003-10       Impact factor: 5.994

Review 4.  ELISA versus PCR for diagnosis of chronic Chagas disease: systematic review and meta-analysis.

Authors:  Pedro E A A Brasil; Liane De Castro; Alejandro M Hasslocher-Moreno; Luiz H C Sangenis; José U Braga
Journal:  BMC Infect Dis       Date:  2010-11-25       Impact factor: 3.090

5.  Trypanosoma cruzi parasitemia in chronic Chagas disease: Insights from hierarchical modeling.

Authors:  Fernando Abad-Franch
Journal:  PLoS Negl Trop Dis       Date:  2022-08-04

6.  T lymphocytes from chagasic patients are activated but lack proliferative capacity and down-regulate CD28 and CD3ζ.

Authors:  Nicolás A Giraldo; Natalia I Bolaños; Adriana Cuellar; Nubia Roa; Zulma Cucunubá; Fernando Rosas; Víctor Velasco; Concepción J Puerta; John M González
Journal:  PLoS Negl Trop Dis       Date:  2013-01-31

Review 7.  Commercial enzyme-linked immunosorbent assay versuspolymerase chain reaction for the diagnosis of chronic Chagas disease: a systematic review and meta-analysis.

Authors:  Pedro Emmanuel Alvarenga Americano do Brasil; Rodolfo Castro; Liane de Castro
Journal:  Mem Inst Oswaldo Cruz       Date:  2016-01       Impact factor: 2.743

  7 in total

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