Literature DB >> 10225964

The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

B P Eliceiri1, D A Cheresh.   

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Year:  1999        PMID: 10225964      PMCID: PMC408360          DOI: 10.1172/JCI6869

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  18 in total

1.  Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging.

Authors:  D A Sipkins; D A Cheresh; M R Kazemi; L M Nevin; M D Bednarski; K C Li
Journal:  Nat Med       Date:  1998-05       Impact factor: 53.440

Review 2.  Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins.

Authors:  A E Aplin; A Howe; S K Alahari; R L Juliano
Journal:  Pharmacol Rev       Date:  1998-06       Impact factor: 25.468

3.  Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins.

Authors:  B L Bader; H Rayburn; D Crowley; R O Hynes
Journal:  Cell       Date:  1998-11-13       Impact factor: 41.582

4.  Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization.

Authors:  H P Hammes; M Brownlee; A Jonczyk; A Sutter; K T Preissner
Journal:  Nat Med       Date:  1996-05       Impact factor: 53.440

5.  Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity.

Authors:  P C Brooks; S Silletti; T L von Schalscha; M Friedlander; D A Cheresh
Journal:  Cell       Date:  1998-02-06       Impact factor: 41.582

6.  Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis.

Authors:  S Strömblad; J C Becker; M Yebra; P C Brooks; D A Cheresh
Journal:  J Clin Invest       Date:  1996-07-15       Impact factor: 14.808

7.  Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

Authors:  P C Brooks; S Strömblad; L C Sanders; T L von Schalscha; R T Aimes; W G Stetler-Stevenson; J P Quigley; D A Cheresh
Journal:  Cell       Date:  1996-05-31       Impact factor: 41.582

8.  Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

Authors:  P C Brooks; S Strömblad; R Klemke; D Visscher; F H Sarkar; D A Cheresh
Journal:  J Clin Invest       Date:  1995-10       Impact factor: 14.808

9.  An antagonist of integrin alpha v beta 3 prevents maturation of blood vessels during embryonic neovascularization.

Authors:  C J Drake; D A Cheresh; C D Little
Journal:  J Cell Sci       Date:  1995-07       Impact factor: 5.285

10.  Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis.

Authors:  B P Eliceiri; R Klemke; S Strömblad; D A Cheresh
Journal:  J Cell Biol       Date:  1998-03-09       Impact factor: 10.539

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  133 in total

Review 1.  Anticancer drug targets: approaching angiogenesis.

Authors:  E Keshet; S A Ben-Sasson
Journal:  J Clin Invest       Date:  1999-12       Impact factor: 14.808

Review 2.  How matrix metalloproteinases regulate cell behavior.

Authors:  M D Sternlicht; Z Werb
Journal:  Annu Rev Cell Dev Biol       Date:  2001       Impact factor: 13.827

3.  Crystal structure of the extracellular segment of integrin alpha Vbeta3.

Authors:  J P Xiong; T Stehle; B Diefenbach; R Zhang; R Dunker; D L Scott; A Joachimiak; S L Goodman; M A Arnaout
Journal:  Science       Date:  2001-09-06       Impact factor: 47.728

4.  A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma.

Authors:  Kevin B Kim; Victor Prieto; Richard W Joseph; Abdul H Diwan; Gary E Gallick; Nicholas E Papadopoulos; Agop Y Bedikian; Luis H Camacho; Patrick Hwu; Chaan S Ng; Wei Wei; Marcella M Johnson; Sabine M Wittemer; Anna Vardeleon; Aaron Reckeweg; A Dimitrios Colevas
Journal:  Melanoma Res       Date:  2012-08       Impact factor: 3.599

5.  Vascular density and endothelial cell expression of integrin alpha v beta 3 and E-selectin in murine tumours.

Authors:  Johanne Seguin; Céline Nicolazzi; Nathalie Mignet; Daniel Scherman; Guy G Chabot
Journal:  Tumour Biol       Date:  2012-06-07

6.  Sustained expression of homeobox D10 inhibits angiogenesis.

Authors:  Connie Myers; Aubri Charboneau; Irene Cheung; Douglas Hanks; Nancy Boudreau
Journal:  Am J Pathol       Date:  2002-12       Impact factor: 4.307

Review 7.  Positron emission tomography (PET): expanding the horizons of oncology drug development.

Authors:  Lisa A Hammond; Louis Denis; Umber Salman; Paul Jerabek; Charles R Thomas; John G Kuhn
Journal:  Invest New Drugs       Date:  2003-08       Impact factor: 3.850

8.  Coordinated regulation and colocalization of alphav integrin and its activating enzyme proprotein convertase PC5 in vivo.

Authors:  Philipp Stawowy; Kristof Graf; Stephan Goetze; Mattias Roser; Michel Chrétien; Nabil G Seidah; Eckart Fleck; Mieczyslaw Marcinkiewicz
Journal:  Histochem Cell Biol       Date:  2003-02-20       Impact factor: 4.304

Review 9.  Manipulating the microvasculature and its microenvironment.

Authors:  Laxminarayanan Krishnan; Carlos C Chang; Sara S Nunes; Stuart K Williams; Jeffrey A Weiss; James B Hoying
Journal:  Crit Rev Biomed Eng       Date:  2013

10.  Expression order of alpha-v and beta-3 integrin subunits in the N-methyl-N-nitrosourea-induced rat mammary tumor model.

Authors:  Robabeh Rezaeipoor; Eric J Chaney; Amy L Oldenburg; Stephen A Boppart
Journal:  Cancer Invest       Date:  2009-06       Impact factor: 2.176

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